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Benign prostatic hyperplasia
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Relevance of Testosterone Levels
Just a general enquiry to all you knowledgeable people out there. On numerous occasions I have seen posts were people when replying have enquired what the individuals testosterone levels where, or that they should get them checked. Now we all know that testosterone feeds PC (and I assume that high
Just a general enquiry to all you knowledgeable people out there. On numerous occasions I have seen posts were people when replying have enquired what the individuals testosterone levels where, or that they should get them checked. Now we all know that testosterone feeds PC (and I assume that high
Trident3
in
Prostate Cancer Network
1 year ago
11 days after 1st Lupron jab-no side effects
It's been 11 days since my first Lupron jab, (1-month dosage) and I am not feeling a single side effect. Not only that, I didn't feel the injection in my hip, nor any soreness afterwards. Nothing. No Casodex. No flare. When I went for the jab my PSA was 10.6 and my T-level was 354. I'm wondering if
It's been 11 days since my first Lupron jab, (1-month dosage) and I am not feeling a single side effect. Not only that, I didn't feel the injection in my hip, nor any soreness afterwards. Nothing. No Casodex. No flare. When I went for the jab my PSA was 10.6 and my T-level was 354. I'm wondering if
Hidden
in
Advanced Prostate Cancer
11 months ago
Do I need lymph node dissection?
Had LAPR in beginning of June. Prior to LARP: PSA 6.2, Biopsy: 3+4 with 40% GG4. Histology report after LARP upgraded the cancer to 4+3 with 70% GG4. In addition, Intraductal carcinoma and Cribriform morphology of GG4 is identified. (EPE: negative, SV: negative, bladder neck and lymph vascular invasion
Had LAPR in beginning of June. Prior to LARP: PSA 6.2, Biopsy: 3+4 with 40% GG4. Histology report after LARP upgraded the cancer to 4+3 with 70% GG4. In addition, Intraductal carcinoma and Cribriform morphology of GG4 is identified. (EPE: negative, SV: negative, bladder neck and lymph vascular invasion
FMOH_N
in
Prostate Cancer Network
11 months ago
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Medical OR chemical castration
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Stevegr
in
Advanced Prostate Cancer
9 months ago
FYI: New data on progression of visceral mets without PSA progression (discordance) and ARAT/docetaxel therapy
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
SeosamhM
in
Advanced Prostate Cancer
11 months ago
RISING PSA 2 YEARS POST EBRT/ADT
Two years post EBRT plus 6 months ADT. Meeting with Oncologist in a few weeks and am wondering what he is going to make of the following PSA progression. Sept 2022 - 0.29 March 2023- 0.56 June 2023 - 0.97 Sept 2023 - 1.77 Testosterone went from near zero post ADT back to 483 in Sept 2022 and
Two years post EBRT plus 6 months ADT. Meeting with Oncologist in a few weeks and am wondering what he is going to make of the following PSA progression. Sept 2022 - 0.29 March 2023- 0.56 June 2023 - 0.97 Sept 2023 - 1.77 Testosterone went from near zero post ADT back to 483 in Sept 2022 and
Waldo13
in
Prostate Cancer Network
11 months ago
CCNA2
New paper below [1]. I was intrigued by the title: "
Comprehensive analysis of the progression mechanisms of CRPC and its inhibitor discovery based on machine learning algorithms
" "
CCNA2
and CKS2 were identified as promising biomarkers ..." "These potential biomarkers were further
New paper below [1]. I was intrigued by the title: "
Comprehensive analysis of the progression mechanisms of CRPC and its inhibitor discovery based on machine learning algorithms
" "
CCNA2
and CKS2 were identified as promising biomarkers ..." "These potential biomarkers were further
pca2004
in
Fight Prostate Cancer
1 year ago
If it doesn't make you feel bad, is it working?
Background: My husband recently received his fourth docetaxel treatment. He has mets to bones and lymph nodes and has had two SBRT sessions to bone and prostate which significantly reduced both pain and node size. He has "failed" both apalutamide and abiraterone and is officially castrate resistant.
Background: My husband recently received his fourth docetaxel treatment. He has mets to bones and lymph nodes and has had two SBRT sessions to bone and prostate which significantly reduced both pain and node size. He has "failed" both apalutamide and abiraterone and is officially castrate resistant.
MiaAmia
in
Advanced Prostate Cancer
11 months ago
Brain metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
pca2004
in
Fight Prostate Cancer
11 months ago
AUA 2023: PSA Response and Time-to-Castration Resistance Among Patients with mCSPCa Initiated on Apalutamide, Enzalutamide, or Abiraterone
The objective of this study was to describe a “real-world” experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
The objective of this study was to describe a “real-world” experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
skiingfiend
in
Advanced Prostate Cancer
11 months ago
PSA post RP - interpretation please
My husband just got this as part of his lab report almost 7 weeks post RP. Hasn't heard from doc yet. Can someone explain what F/T PSA >0.00 means? And 55% probability of prostate cancer?? Specimen ID: 1 Collection Start Date: 10/25/2023 3:43 P FREE PSA [FREEPSA] 0.00 ng/mL Free/Total P S A [F/
My husband just got this as part of his lab report almost 7 weeks post RP. Hasn't heard from doc yet. Can someone explain what F/T PSA >0.00 means? And 55% probability of prostate cancer?? Specimen ID: 1 Collection Start Date: 10/25/2023 3:43 P FREE PSA [FREEPSA] 0.00 ng/mL Free/Total P S A [F/
studioj
in
Prostate Cancer Network
9 months ago
Surgery While on Xtandi/Eligard
I have been on Xtandi/Eligard now for about 5 months. At a psa of around 1.9 last March psma pet picked up 3 nodules in my lungs. All less than a cm. I am hormone sensitive and my current psa is undetectable. This July I had a ct scan of chest/abdomen/pelvis. The mets in the lung have decreased in size
I have been on Xtandi/Eligard now for about 5 months. At a psa of around 1.9 last March psma pet picked up 3 nodules in my lungs. All less than a cm. I am hormone sensitive and my current psa is undetectable. This July I had a ct scan of chest/abdomen/pelvis. The mets in the lung have decreased in size
Hidden
in
Advanced Prostate Cancer
11 months ago
CTC MEANING
I entered the SPLASH trial in Spet 2022 and had my first treatment in Dec 2022. I had mets from PSMA scan aZhang at Moffitt. He thought I had responded rather well to the treaments and suggested I shoudl get a CTC (curculating tumor) test and as long as that was under 5 perhaps Provenge treatment. The
I entered the SPLASH trial in Spet 2022 and had my first treatment in Dec 2022. I had mets from PSMA scan aZhang at Moffitt. He thought I had responded rather well to the treaments and suggested I shoudl get a CTC (curculating tumor) test and as long as that was under 5 perhaps Provenge treatment. The
Joeym1040
in
Advanced Prostate Cancer
11 months ago
Rapidly Rising PSA
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
CrocodileShoes
in
Advanced Prostate Cancer
11 months ago
PSA drop after ADT
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
John347
in
Advanced Prostate Cancer
11 months ago
PSA went from 0.97 to 0.99 during chemo treatments. Should we be concerned?
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Jdhanoa
in
Advanced Prostate Cancer
11 months ago
PSA seasonality
I am mounting a theory that has to do with increased PSADT during winter vs summer time. For this reason I analyzed my old PSA readings during the 2+ years before starting Bicalutamide. I divided the year into two halfs assigning winter as the period starting on the autumnal equinox and ending on the
I am mounting a theory that has to do with increased PSADT during winter vs summer time. For this reason I analyzed my old PSA readings during the 2+ years before starting Bicalutamide. I divided the year into two halfs assigning winter as the period starting on the autumnal equinox and ending on the
Justfor_
in
Fight Prostate Cancer
11 months ago
PSA going in wrong direction
Finished 37 radiation treatments to aortic lymph nodes a week ago after a PSMA scan highlighted three avid nodes in August. Started orgovyx three weeks ago and nubeqa four days ago. Visit with my MO revealed a PSA increase from .21 in August to .7 today. Seems the numbers are defying the treatment.
Finished 37 radiation treatments to aortic lymph nodes a week ago after a PSMA scan highlighted three avid nodes in August. Started orgovyx three weeks ago and nubeqa four days ago. Visit with my MO revealed a PSA increase from .21 in August to .7 today. Seems the numbers are defying the treatment.
Jvaughan0
in
Advanced Prostate Cancer
9 months ago
puzzled with Orgovyx
First of all my score was 7(3+4) 6.5 to 7 years ago. I was taking nutrients and vitamins to fight the cancer which was working great until I had kidney stone surgery. Psa shot up to 101 which is when I stopped my self medication and then started the casadex which then brought my PSA down to 3. I was
First of all my score was 7(3+4) 6.5 to 7 years ago. I was taking nutrients and vitamins to fight the cancer which was working great until I had kidney stone surgery. Psa shot up to 101 which is when I stopped my self medication and then started the casadex which then brought my PSA down to 3. I was
woppaginny
in
Advanced Prostate Cancer
11 months ago
Rutin / Senolytics
New paper below [1]. In 1995, Edward Giovannucci was responsible for triggering the PCa lycopene craze. "Of 46 vegetables and fruits or related products, four were significantly associated with lower prostate cancer risk; of the four--tomato sauce, tomatoes, and pizza, but not strawberries--were
New paper below [1]. In 1995, Edward Giovannucci was responsible for triggering the PCa lycopene craze. "Of 46 vegetables and fruits or related products, four were significantly associated with lower prostate cancer risk; of the four--tomato sauce, tomatoes, and pizza, but not strawberries--were
pca2004
in
Fight Prostate Cancer
1 year ago
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