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FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
cujoe
in
CLL Support
7 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
7 months ago
Zencor & XmAb
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
AllenMarco
in
Advanced Prostate Cancer
7 months ago
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trial for Debbie Summergold2
for got to post the number of the trialDS6000-A-U101 clinical trial, NCT 04707248.
for got to post the number of the trialDS6000-A-U101 clinical trial, NCT 04707248.
Summergold2
in
My Ovacome
7 months ago
Atrial Flutter is new to me
What seems to help reduce
atrial
flutter
?
What seems to help reduce
atrial
flutter
?
Archaeolog
in
AF Association
2 years ago
What would you expect?
Hi Everyone, Just thought I’d ask here as the help I’ve received on here has been invaluable. Since my Cardioversion in Jan 2022 I have been in a sinus rhythm. I was originally told prior to the Cardioversion that if 6 months after I’m still in a sinus rhythm. I would be able to come off the edoxaban
Hi Everyone, Just thought I’d ask here as the help I’ve received on here has been invaluable. Since my Cardioversion in Jan 2022 I have been in a sinus rhythm. I was originally told prior to the Cardioversion that if 6 months after I’m still in a sinus rhythm. I would be able to come off the edoxaban
wordzo
in
AF Association
11 months ago
Post ablation short of breath
I am 74 years old. I had a catheter ablation 3 days ago having been in permanent Afib for 5 months. I have suffered from asthma since childhood & have an FEV of a 90 year old, or so I'm told. Nevertheless I was 3 months trekking in Nepal recently (Nov to January this year), hiking to 5,400 metres and
I am 74 years old. I had a catheter ablation 3 days ago having been in permanent Afib for 5 months. I have suffered from asthma since childhood & have an FEV of a 90 year old, or so I'm told. Nevertheless I was 3 months trekking in Nepal recently (Nov to January this year), hiking to 5,400 metres and
jnbee
in
Atrial Fibrillation Support
11 months ago
Vitamin B2 Deficiency Can Cause B6 Toxicity! PWP Are Commonly Deficient In B2.
Vitamin B6 recycling. Image credit https://www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations
Vitamin B6 recycling. Image credit https://www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations
park_bear
in
Cure Parkinson's
7 months ago
A DNA test, a book and a diet - my AFib Eureka moment !
First I wanted to say what a fantastic group this is and just how much it has supported, reassured and lifted me on my Afib journey, it’s been invaluable I’m a 61 year old woman with paroxysmal lone Afib, possibly SVT too. My story in brief is that I was diagnosed 3 years ago after my Fitbit showed
First I wanted to say what a fantastic group this is and just how much it has supported, reassured and lifted me on my Afib journey, it’s been invaluable I’m a 61 year old woman with paroxysmal lone Afib, possibly SVT too. My story in brief is that I was diagnosed 3 years ago after my Fitbit showed
Dyldog
in
Arrhythmia Alliance
11 months ago
A DNA test, a book and a diet - AFib Eureka moment !
First I wanted to say what a fantastic group this is and just how much it has supported, reassured and lifted me on my AFib journey, it’s been invaluable I’m a 61 year old woman with paroxysmal lone AFib, possibly SVT too. My story in brief is that I was diagnosed 3 years ago after my Fitbit showed
First I wanted to say what a fantastic group this is and just how much it has supported, reassured and lifted me on my AFib journey, it’s been invaluable I’m a 61 year old woman with paroxysmal lone AFib, possibly SVT too. My story in brief is that I was diagnosed 3 years ago after my Fitbit showed
Dyldog
in
AF Association
11 months ago
Zhittya the drug treatment that should address the root causes of the disease and not just the symptoms.
It seems there is a new drug being developed by ZHITTYA GENESIS MEDICINE Please refer to the link below https://www.zgm.care/news/november-2023-update From the website: Parkinson's Disease It is estimated that over one million Americans are affected by Parkinson's Disease. Recent research proposes
It seems there is a new drug being developed by ZHITTYA GENESIS MEDICINE Please refer to the link below https://www.zgm.care/news/november-2023-update From the website: Parkinson's Disease It is estimated that over one million Americans are affected by Parkinson's Disease. Recent research proposes
Bianhua
in
Cure Parkinson's
7 months ago
PAF - move to PiP only
Hi Can anyone tell me of their experiences of moving from daily medication (Flecainide) to PiP only? Heart attack in 2019, out of the blue - fit & healthy. Investigations - no real culprit - eventually a few months later, after symptoms & further investigations, diagnosed with paroxysmal AFib. Basically
Hi Can anyone tell me of their experiences of moving from daily medication (Flecainide) to PiP only? Heart attack in 2019, out of the blue - fit & healthy. Investigations - no real culprit - eventually a few months later, after symptoms & further investigations, diagnosed with paroxysmal AFib. Basically
AAJJTt
in
Atrial Fibrillation Support
11 months ago
Two interesting articles
Here are links to two interesting articles. The first one details the benefits of exercise in preventing AF (it’s not clear if this applies to those who already have AF). The second-an older one which has been posted before but can probably stand repetition-details the negative effects of even small
Here are links to two interesting articles. The first one details the benefits of exercise in preventing AF (it’s not clear if this applies to those who already have AF). The second-an older one which has been posted before but can probably stand repetition-details the negative effects of even small
Samazeuilh2
in
AF Association
11 months ago
What is Left Atrial Rhythm and is it related to Afib?
I have paroxysmal Afib, which appears to be well managed with Flecainide and Metoprolol. I am having an unrelated medical procedure next week so my anaesthetist sent me for an ECG, which I had to drop back to her office. After getting the ECG done by a nurse at my local GP's rooms, the nurse took the
I have paroxysmal Afib, which appears to be well managed with Flecainide and Metoprolol. I am having an unrelated medical procedure next week so my anaesthetist sent me for an ECG, which I had to drop back to her office. After getting the ECG done by a nurse at my local GP's rooms, the nurse took the
bean_counter27
in
Atrial Fibrillation Support
11 months ago
Bisoprolol - weird side effects on low dose?
I am wondering if I have developed
atrial
flutter
. I also get random stabbing chest pains on the left side, which are scary. Had an x-ray recently which found no issues in my heart or lungs. Anyway, the point of all this...
I am wondering if I have developed
atrial
flutter
. I also get random stabbing chest pains on the left side, which are scary. Had an x-ray recently which found no issues in my heart or lungs. Anyway, the point of all this...
tokenwelshman
in
AF Association
1 year ago
Does anyone have CtDna blood test added In their monitoring routine?
Hi! Kim 43 MBC since 3/2021. I do alot of reading of clinical trials and medical journals. I found this CtDna blood test that SUPPOSEDLY detects cancer cells in the blood up to 10 months sooner than a Petscan. My Oncologist didn't know about this testing so after fielding out all the companies that do
Hi! Kim 43 MBC since 3/2021. I do alot of reading of clinical trials and medical journals. I found this CtDna blood test that SUPPOSEDLY detects cancer cells in the blood up to 10 months sooner than a Petscan. My Oncologist didn't know about this testing so after fielding out all the companies that do
KimberlyB40
in
SHARE Metastatic Breast Cancer
7 months ago
Flecainide, Diltiazem and Shortness of Breath
Anyone get shortness of breath (SOB) from Flecainide and/or Diltiazem -- not right away, but months later? For the first six months on both drugs, I had no SOB. For the second six months I had SOB. Now that I stopped both drugs, it seems better. Could be a coincidence, but looking for group experiences
Anyone get shortness of breath (SOB) from Flecainide and/or Diltiazem -- not right away, but months later? For the first six months on both drugs, I had no SOB. For the second six months I had SOB. Now that I stopped both drugs, it seems better. Could be a coincidence, but looking for group experiences
mjames1
in
Atrial Fibrillation Support
1 year ago
Ambroxol update
I just received this from PD front line: Dear Mr..In January of this year, Cure Parkinson’s and partners announced funding for the starting up of a Phase 3 clinical trial to evaluate the disease modifying potential of a cough medicine called ambroxol in people with Parkinson’s. Preclinical data in models
I just received this from PD front line: Dear Mr..In January of this year, Cure Parkinson’s and partners announced funding for the starting up of a Phase 3 clinical trial to evaluate the disease modifying potential of a cough medicine called ambroxol in people with Parkinson’s. Preclinical data in models
CuriousMe12
in
Cure Parkinson's
7 months ago
Many thanks to the hundreds of you who tried Vitawaves, the Clinical Trial Navigator and the Patient Navigator
Many thanks to the hundreds of you who tried, Vitawaves,the Clinical Trial Navigator and the Patient Navigator All three are now launched. I hope to see thousands more using these tools. Malecare will be launching two more novel platforms, utilizing our AI engine and each filling needs many have requested
Many thanks to the hundreds of you who tried, Vitawaves,the Clinical Trial Navigator and the Patient Navigator All three are now launched. I hope to see thousands more using these tools. Malecare will be launching two more novel platforms, utilizing our AI engine and each filling needs many have requested
Darryl
Partner
in
Advanced Prostate Cancer
7 months ago
Being Thankful----Year 6
Greetings FPC members: Each year, I try and post at holiday times of reasons to be thankful regarding PCa developments, and I am thankful for so many things that I have, but we can all be thankful for : 1) NCI and it's support of clinical trials ( including the trials of cancer drugs like RRX-001
Greetings FPC members: Each year, I try and post at holiday times of reasons to be thankful regarding PCa developments, and I am thankful for so many things that I have, but we can all be thankful for : 1) NCI and it's support of clinical trials ( including the trials of cancer drugs like RRX-001
NPfisherman
in
Fight Prostate Cancer
7 months ago
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