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LU-177 I&T, FAILURE?
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
john4803
in
Advanced Prostate Cancer
9 months ago
Update on my father
I just wanted to post a quick update on my father. He has metastatic castrate resistant prostate cancer. He’s been on ADT - Eligard shots every 3 months and prednisone + zytiga everyday. It’s challenging as I work with him and see all the ins and outs of his behaviour while on those meds. He remains
I just wanted to post a quick update on my father. He has metastatic castrate resistant prostate cancer. He’s been on ADT - Eligard shots every 3 months and prednisone + zytiga everyday. It’s challenging as I work with him and see all the ins and outs of his behaviour while on those meds. He remains
jberg22
in
Advanced Prostate Cancer
9 months ago
PSA rising
Just got this report from PSMA scan. Increased size of a few mildly tracer avid aorto-caval lymphnodes. The largest of these nodes measures 0.5 cm in short axis (image 204), previously measured 0.2 cm. Meet with MO tomorrow. I am 10 years in. Prostatectomy, bed radiation, and two years ago, whole
Just got this report from PSMA scan. Increased size of a few mildly tracer avid aorto-caval lymphnodes. The largest of these nodes measures 0.5 cm in short axis (image 204), previously measured 0.2 cm. Meet with MO tomorrow. I am 10 years in. Prostatectomy, bed radiation, and two years ago, whole
Jvaughan0
in
Advanced Prostate Cancer
9 months ago
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Appreciate feedback on my going forward plan & timing
After 3 years from robotic RP with a 5+4 Gleason score, my PSA moved from zero to .099 ng/mL. See my profile for more data.
August
– Meetings with expert Dr. Collins (Georgetown). Wants to move fast with 5 days for 5 weeks radiation with six months of ADT (Orgovyx) due to my high Gleason from
After 3 years from robotic RP with a 5+4 Gleason score, my PSA moved from zero to .099 ng/mL. See my profile for more data.
August
– Meetings with expert Dr. Collins (Georgetown). Wants to move fast with 5 days for 5 weeks radiation with six months of ADT (Orgovyx) due to my high Gleason from
Murk
in
Prostate Cancer Network
9 months ago
Revisiting Intermittent Therapy in Metastatic Prostate Cancer
The A-Dream Phase 2 trial is taking a second look at intermittent therapy for mHSPCa. In the study they hope to answer the question 1. Can intermittent therapy (a break from treatment) for high responders (PSA < .2 over 18-24 mos) on ADT+ARPi be more effective than continuous ADT (the current standard
The A-Dream Phase 2 trial is taking a second look at intermittent therapy for mHSPCa. In the study they hope to answer the question 1. Can intermittent therapy (a break from treatment) for high responders (PSA < .2 over 18-24 mos) on ADT+ARPi be more effective than continuous ADT (the current standard
skiingfiend
in
Advanced Prostate Cancer
9 months ago
Pet scan vs CT scan
Hi fellow warriors, I've just had a phone appointment with my Oncologist my PSA is 0.7 and started to go up but not high enough to warrant having a Scan at the moment.My problem is she doesn't think she will be able to put me forward for a Pet scan as I have already had a couple in the past and with
Hi fellow warriors, I've just had a phone appointment with my Oncologist my PSA is 0.7 and started to go up but not high enough to warrant having a Scan at the moment.My problem is she doesn't think she will be able to put me forward for a Pet scan as I have already had a couple in the past and with
Chubby42
in
Advanced Prostate Cancer
9 months ago
excuse me asking. Brain fog.
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Stifffingers
in
PMRGCAuk
9 months ago
taxotere and PSA
adt stopped 9/22, daralutamide mono therapy until 7/23. Three rounds of docetaxel until 7/17/23. PSA rose from 4.9 to 5.1. PSMA scan showed decline in bone Mets. Tried a bit of fasting. Just switched to cabitaxel due to seeming failure of docetaxel based on PSA rise. Wondering if PSA increase was the
adt stopped 9/22, daralutamide mono therapy until 7/23. Three rounds of docetaxel until 7/17/23. PSA rose from 4.9 to 5.1. PSMA scan showed decline in bone Mets. Tried a bit of fasting. Just switched to cabitaxel due to seeming failure of docetaxel based on PSA rise. Wondering if PSA increase was the
CWT53
in
Advanced Prostate Cancer
9 months ago
Indomethacin - resenisitize to Enza
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
Hidden
in
Fight Prostate Cancer
9 months ago
Surviving in retirement
At age 52 I was diagnosed with stage 3 Multiple Myeloma ; after 2 bone marrow transplants in 2007 & 2009 I was able to continue my engineering job until age 65. At 66 my PSA was 3400 with Gleason score 4 ; started Docetaxel and Jevtana until July 23 ; Now on Pluvicto have 5 more treatments to
At age 52 I was diagnosed with stage 3 Multiple Myeloma ; after 2 bone marrow transplants in 2007 & 2009 I was able to continue my engineering job until age 65. At 66 my PSA was 3400 with Gleason score 4 ; started Docetaxel and Jevtana until July 23 ; Now on Pluvicto have 5 more treatments to
chipspesto
in
Advanced Prostate Cancer
9 months ago
Simple Prostatectomy
Hello everyone , My father was diagnosed with locally advanced prostate cancer in March of 2021, PSA 6900 … After 3 months on Eligard his PSA dropped to 0.6 and it has been so for more than 2 years now. He has been on foley catheter since March of 2021 because of a very enlarged prostate and has refused
Hello everyone , My father was diagnosed with locally advanced prostate cancer in March of 2021, PSA 6900 … After 3 months on Eligard his PSA dropped to 0.6 and it has been so for more than 2 years now. He has been on foley catheter since March of 2021 because of a very enlarged prostate and has refused
naples2021
in
Advanced Prostate Cancer
9 months ago
ADT duration
I have locally contained G9 discovered July as PSA in June 2022 rose to 6.9 , 6 months after HIFU In December 2021. Immediately started Bicalutimide 150 3rd August 2022 and planned radiotherapy for end of November 2022 after clear PSMA. For various reasons I was on bicalutimide for longer than
I have locally contained G9 discovered July as PSA in June 2022 rose to 6.9 , 6 months after HIFU In December 2021. Immediately started Bicalutimide 150 3rd August 2022 and planned radiotherapy for end of November 2022 after clear PSMA. For various reasons I was on bicalutimide for longer than
SimMartin
in
Advanced Prostate Cancer
9 months ago
Long survivors with ADT + Xtandi (Enzulatamide)
5 years after RPE and RT my PSA is rising again. I am advised to start ADT + Xtandi. Who are longest still on this combination without getting castration resistant?
5 years after RPE and RT my PSA is rising again. I am advised to start ADT + Xtandi. Who are longest still on this combination without getting castration resistant?
ElemanJ
in
Advanced Prostate Cancer
9 months ago
Is Xtandi Failing?
Background: Diagnosis in Jan/2020, PSA 577, Gleason 9, mets to lymph nodes and bones Started Firmagon immediately as well as chemo, 6 cycles of Docetaxel. Followed this by radiation to the prostate. PSA dropped pretty quick and eventually into the teens and single digits, lowest was 4.5 back in January
Background: Diagnosis in Jan/2020, PSA 577, Gleason 9, mets to lymph nodes and bones Started Firmagon immediately as well as chemo, 6 cycles of Docetaxel. Followed this by radiation to the prostate. PSA dropped pretty quick and eventually into the teens and single digits, lowest was 4.5 back in January
GTTown
in
Advanced Prostate Cancer
9 months ago
PSMA scan with PSA < 0.20?
Has anyone had a PSMA scan before PSA reached 0.20? If so, were any tumors detected?
Has anyone had a PSMA scan before PSA reached 0.20? If so, were any tumors detected?
ron_bucher
in
Advanced Prostate Cancer
9 months ago
who out there has been on Lupron and abiraterone?
who out there has been on Lupron and abiraterone? Who is the longest survivor out there in terms of not transitioning to castrate resistant. I just started treatment 6/15/23 and am trying to hit it with additional therapies as my PSA declines. Vit c. Melatonin. Ivermectin. I am going to start baking
who out there has been on Lupron and abiraterone? Who is the longest survivor out there in terms of not transitioning to castrate resistant. I just started treatment 6/15/23 and am trying to hit it with additional therapies as my PSA declines. Vit c. Melatonin. Ivermectin. I am going to start baking
Nowhereman9
in
Advanced Prostate Cancer
9 months ago
Prostatitis or PCA or both?
30yo, frequent urination (sometimes no volume), back ache, both symptoms intermittent. MRI Pirads 2, DRE negative, 20cc some calcifications. Positive culture e faecalis sensitive to levo. PSA rising even with levo-- from 8-11-9-13. Low %free at one point 5% but also 12% the the next test around. I did
30yo, frequent urination (sometimes no volume), back ache, both symptoms intermittent. MRI Pirads 2, DRE negative, 20cc some calcifications. Positive culture e faecalis sensitive to levo. PSA rising even with levo-- from 8-11-9-13. Low %free at one point 5% but also 12% the the next test around. I did
4194ujr12r21312
in
Men's Health Forum
9 months ago
Is abiraterone failing? What's next
I started abiraterone acetate 1000mg along with prednisolone from 25/2/22 that time psa level was 9.40 highest since 2018, psa decreased to 0.02 in feb,2023 now on 5 aug it has risen to 4.32, does it mean abiraterone did it's job and i need to stop this....
I started abiraterone acetate 1000mg along with prednisolone from 25/2/22 that time psa level was 9.40 highest since 2018, psa decreased to 0.02 in feb,2023 now on 5 aug it has risen to 4.32, does it mean abiraterone did it's job and i need to stop this....
Rafithussain
in
Advanced Prostate Cancer
9 months ago
PSMA - how is this?
Click link for animated video: https://ibb.co/vP7p8XH My recent PSMA is shown with 4 images in order. Right-click image, open in new tab to zoom in. What do you see? Does this look bad news to you or of serious concern? Would you suggest RP, radiation, or AS? My urologist seems to have taken this PSMA
Click link for animated video: https://ibb.co/vP7p8XH My recent PSMA is shown with 4 images in order. Right-click image, open in new tab to zoom in. What do you see? Does this look bad news to you or of serious concern? Would you suggest RP, radiation, or AS? My urologist seems to have taken this PSMA
Thunderball1
in
Advanced Prostate Cancer
9 months ago
Treatment Question
Hi to all, my dad (age 62) was diagnosed with Stage 4 prostate cancer with multiple bone metastases in October 2022. He is also BRCA2 positive. He received 6 doses of docetaxel which he completed on 1/30/2023 and has also been taking apalutamide daily and eligard injections every 3 months. His PSA on
Hi to all, my dad (age 62) was diagnosed with Stage 4 prostate cancer with multiple bone metastases in October 2022. He is also BRCA2 positive. He received 6 doses of docetaxel which he completed on 1/30/2023 and has also been taking apalutamide daily and eligard injections every 3 months. His PSA on
Juju0713
in
Advanced Prostate Cancer
9 months ago
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