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Christmas Chuckle
Next year will you please remind us To have
Alka
-
Seltzer
handy
Next year will you please remind us To have
Alka
-
Seltzer
handy
Paul_and_Sue_Wood
in
Multiple System Atrophy Trust
5 months ago
Besremi trial
Two New Trials Testing Ropeginterferon (Besremi) in PV and ETMar 3, 2023John Mascarenhas, MDAssociate Professor & Director of the Adult Leukemia Program0 seconds of 8 minutes, 40 secondsDESCRIPTIONTRANSCRIPTDr. Mascarenhas: Hi, I'm John Mascarenhas, a professor of medicine at the Icahn School of Medicine
Two New Trials Testing Ropeginterferon (Besremi) in PV and ETMar 3, 2023John Mascarenhas, MDAssociate Professor & Director of the Adult Leukemia Program0 seconds of 8 minutes, 40 secondsDESCRIPTIONTRANSCRIPTDr. Mascarenhas: Hi, I'm John Mascarenhas, a professor of medicine at the Icahn School of Medicine
wateron
in
MPN Voice
3 months ago
Real world experience with Besremi in ET and PV following exposure to Pegasys.
Abstract Despite widespread use of Pegylated forms of Inteferon in the management of Myeloproliferative Neoplasms (MPN), most clinicians have experience predominantly with peginterferon alfa-2a (Pegasys). Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN; Besremi), was recommended
Abstract Despite widespread use of Pegylated forms of Inteferon in the management of Myeloproliferative Neoplasms (MPN), most clinicians have experience predominantly with peginterferon alfa-2a (Pegasys). Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN; Besremi), was recommended
Manouche
in
MPN Voice
5 months ago
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Keeping Interferon refrigerated
Hi, I've recently started taking Peginterferon alfa-2a, and I keep it in my fridge because that's what the instructions say. I'm going to visit my girlfriend in Scotland a week tomorrow. My journey is going to take two days, so I'll leave home on Saturday morning, stay in a hotel halfway on Saturday
Hi, I've recently started taking Peginterferon alfa-2a, and I keep it in my fridge because that's what the instructions say. I'm going to visit my girlfriend in Scotland a week tomorrow. My journey is going to take two days, so I'll leave home on Saturday morning, stay in a hotel halfway on Saturday
little_oblivion
in
MPN Voice
8 months ago
Interferons as the First Choice of Cytoreduction in ET and PV
»Interferons are a group of cytokines with immunomodulatory properties and were the first immune therapies used in the treatment of cancers, including hematologic malignancies. Use of standard interferon alfa-2b for MPN treatment has been limited by its difficulty in administration and adverse effect
»Interferons are a group of cytokines with immunomodulatory properties and were the first immune therapies used in the treatment of cancers, including hematologic malignancies. Use of standard interferon alfa-2b for MPN treatment has been limited by its difficulty in administration and adverse effect
Manouche
in
MPN Voice
9 months ago
Cost of Interferon Alfa 2a
Does Interferon Alfa 2a (Pegasus) cost $1000 for 180mcg/ml ?? Without insurance?
Does Interferon Alfa 2a (Pegasus) cost $1000 for 180mcg/ml ?? Without insurance?
MrThara
in
MPN Voice
1 year ago
Peg injections - two in one day
Hi all, I’m on peginterferon Alfa-2a for ET and a few weeks ago my dose was increased to 180mg. The hospital pharmacy deliver my medication and I can only assume they’ve ran out of 180mg syringes as I’ve been sent about 8 boxes of 90mg pre filled syringes meaning I’m expected to do 2 injections after
Hi all, I’m on peginterferon Alfa-2a for ET and a few weeks ago my dose was increased to 180mg. The hospital pharmacy deliver my medication and I can only assume they’ve ran out of 180mg syringes as I’ve been sent about 8 boxes of 90mg pre filled syringes meaning I’m expected to do 2 injections after
FashionLover
in
MPN Voice
1 year ago
Greater Understanding of PV, ET Drives Potential New Treatment Options
“Continued high-impact research may soon foster the development of disease-modifying therapies for PV and ET and satisfy this need for the optimal management of patients with these MPNs,” they said. Researchers are also determining how to best optimize current treatment options, including JAK inhibitors
“Continued high-impact research may soon foster the development of disease-modifying therapies for PV and ET and satisfy this need for the optimal management of patients with these MPNs,” they said. Researchers are also determining how to best optimize current treatment options, including JAK inhibitors
Manouche
in
MPN Voice
2 years ago
Roxadustat and thyroid-stimulating hormone suppression
Just posting this so that it has been posted. I have my doubts it will be relevant to more than a handful - but I could be wrong. [i]
Roxadustat and thyroid-stimulating hormone suppression
Atsuyuki Tokuyama, Hiroyuki Kadoya, Atsushi Obata, Takahiro Obata, Tamaki Sasaki, Naoki Kashihara Clinical
Just posting this so that it has been posted. I have my doubts it will be relevant to more than a handful - but I could be wrong. [i]
Roxadustat and thyroid-stimulating hormone suppression
Atsuyuki Tokuyama, Hiroyuki Kadoya, Atsushi Obata, Takahiro Obata, Tamaki Sasaki, Naoki Kashihara Clinical
helvella
Thyroid UK
in
Thyroid UK
2 years ago
On bone marrow biopsy (BMB)?
Hello everyone, People with PV/ET regularly (e.g., per month) test their blood to keep track of cell counts and other things. How about bone marrow biopsy (BMB)? Are there repeats of BMB test to check changes after the first one that was performed to detect any mutation like JK2 ? If yes, how the results
Hello everyone, People with PV/ET regularly (e.g., per month) test their blood to keep track of cell counts and other things. How about bone marrow biopsy (BMB)? Are there repeats of BMB test to check changes after the first one that was performed to detect any mutation like JK2 ? If yes, how the results
samiris
in
MPN Voice
3 years ago
Dukoral - Cholera Vaccine
.🍸🍸🤠 PS: Taste is not bad, about like
alka
seltzer
.
.🍸🍸🤠 PS: Taste is not bad, about like
alka
seltzer
.
Drphil1938
in
Advanced Prostate Cancer
4 years ago
Pipeline of ataxia related research.
Found a report online being offered for $2000 that summarizes the current pipeline of all known ataxia related drugs. - - - Spinocerebellar Ataxia (SCA) - Companies Involved in Therapeutics Development Bio Blast Pharma Ltd Biohaven Pharmaceutical Holding Company Ltd Cadent Therapeutics Ionis Pharmaceuticals
Found a report online being offered for $2000 that summarizes the current pipeline of all known ataxia related drugs. - - - Spinocerebellar Ataxia (SCA) - Companies Involved in Therapeutics Development Bio Blast Pharma Ltd Biohaven Pharmaceutical Holding Company Ltd Cadent Therapeutics Ionis Pharmaceuticals
sunvox
in
Ataxia UK
5 years ago
Knight five
Myself and a wee Baroness posing with Sir
Alka
Seltzer
Cheesemonger This particular knight was a thrice married man who once went into battle wearing nothing but a smile. He stoutly refused to use a sword and when that tactic finally caught up with him, his replacement was severed.
Myself and a wee Baroness posing with Sir
Alka
Seltzer
Cheesemonger This particular knight was a thrice married man who once went into battle wearing nothing but a smile. He stoutly refused to use a sword and when that tactic finally caught up with him, his replacement was severed.
BaronC
in
Headway
6 years ago
Bloated constipation due to ibs
I've had
alka
seltzer
too which great for short term pain
I've had
alka
seltzer
too which great for short term pain
Deb131
in
IBS Network
6 years ago
Air bubbles in chest, pain, shortness of breath
I seen a lot of people on here with the same symptoms, best thing I have found so far to help is
Alka
Seltzer
. Just to put the word out there for anyone in need, I know how painful this can be. Good luck
I seen a lot of people on here with the same symptoms, best thing I have found so far to help is
Alka
Seltzer
. Just to put the word out there for anyone in need, I know how painful this can be. Good luck
Disclosure
in
Anxiety Support
6 years ago
Only you will get how exciting this is...
Plans are afoot to stock up on immodum,
alka
seltzer
(my go-to pack for glutening disasters). And then a miracle occurs...
Plans are afoot to stock up on immodum,
alka
seltzer
(my go-to pack for glutening disasters). And then a miracle occurs...
Hidden
in
Gluten Free Guerrillas
6 years ago
What is your OTC Painkiller of choice for Migraine (UK)?
By far I find the most effective to be
Alka
Seltzer
, the effect of the aspirin and effervescence does offer *some* relief. That is, only if it's a, say, 1 to 4 (out of 10) non-vomiting migraine pain - not a "monster 10" - then nothing touches the sides. What is your painkiller of choice?
By far I find the most effective to be
Alka
Seltzer
, the effect of the aspirin and effervescence does offer *some* relief. That is, only if it's a, say, 1 to 4 (out of 10) non-vomiting migraine pain - not a "monster 10" - then nothing touches the sides. What is your painkiller of choice?
Moon_Struck
in
National Migraine Centre
7 years ago
Viread, peginterferon alfa-2a more effective in combination for reducing HBsAg
http://www.healio.com/hepatology/chronic-hepatitis/news/online/%7B625d1cdc-2b04-42c8-9e2f-9e73931fc5c6%7D/viread-peginterferon-alfa-2a-more-effective-in-combination-for-reducing-hbsag?utm_source=maestro&utm_medium=email&utm_campaign=hepatology%20news
http://www.healio.com/hepatology/chronic-hepatitis/news/online/%7B625d1cdc-2b04-42c8-9e2f-9e73931fc5c6%7D/viread-peginterferon-alfa-2a-more-effective-in-combination-for-reducing-hbsag?utm_source=maestro&utm_medium=email&utm_campaign=hepatology%20news
kcohen
in
HFI Connect - Hepatitis
8 years ago
Interferon monotherapy effective in patients with HCV thalassemia major
Interferon alfa-2b or pegylated interferon-alfa-2b monotherapies were effective treatment options in patients with hepatitis C virus thalassemia major, according to study results. “IL28B genotype was a strong predictor for sustained virological response, together with splenectomy, age and fibrosis,”
Interferon alfa-2b or pegylated interferon-alfa-2b monotherapies were effective treatment options in patients with hepatitis C virus thalassemia major, according to study results. “IL28B genotype was a strong predictor for sustained virological response, together with splenectomy, age and fibrosis,”
kcohen
in
HFI Connect - Hepatitis
8 years ago
Does Pegylated interferon alfa-2a cure ET? Some paper show yes. Is this credible?
I found a paper Quintás-Cardama A, Kantarjian H, Manshouri T, et al. Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera[J]. Journal of Clinical Oncology, 2009, 27(32): 5418-5424. This show the
I found a paper Quintás-Cardama A, Kantarjian H, Manshouri T, et al. Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera[J]. Journal of Clinical Oncology, 2009, 27(32): 5418-5424. This show the
Midas_
in
MPN Voice
8 years ago
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