Sweet syndrome in the setting of breast cancer

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Sweet syndrome in the setting of breast cancer: A literature review 2024.

34 cases of female patients with breast cancer and Sweet's syndrome (authors used a wide search range from 1950 to 2023).

Triggers for Sweet's syndrome within this setting:

- Surgery (47%)

- Medication (20%)

- Triggered by the cancer itself {paraneoplastic, 20%)

- Radiation therapy (11%).

Depending on the trigger, average time before Sweet's syndrome symptoms appeared:

- Medication (3.3 months)

- Radiation therapy (8.5 months)

- Surgery (4 years and 2 months)

- Paraneoplastic (4 years and 9 months).

26 cases of Sweet's syndrome resolved after treatment with oral steroids (65%) and steroid creams (12%).

How quickly treatments started to work.

- Medication (2.7 days)

- Radiation therapy (7 days)

- Paraneoplastic (10.5 days)

- Surgery (18.5 days)

In 5 cases (paraneoplastic), symptoms came back after inital treatment.

15 case studies mentioned breast cancer type.

- Invasive ductal carcinoma of the breast (47%)

- Metastatic carcinoma (20%)

- Adenocarcinoma (13%)

- Invasive lobular carcinoma (6%)

- Canalicular breast carcinoma (6%)

- Unspecified malignant tumor of the breast (6%). ascopubs.org/doi/10.1200/JC...