SUDDEN increase in Sed rate, or erythrocyte sedimentation rate (ESR

[irishponies]

Hello, I want to thank everyone that shared their personal insights replying to my post "ANCA MPO and Systemic sclerosis positive - Sudden ESR 93". Your comments are invaluable and I appreciate every word. Thank you,

This post is focused on ESR. This is copied directly from the Mayo Clinic web site:

"Sed rate, or erythrocyte sedimentation rate (ESR), is a blood test that can reveal inflammatory activity in your body. A sed rate test isn't a stand-alone diagnostic tool, but it can help your doctor diagnose or monitor the progress of an inflammatory disease."

I have researched and cannot find reports regarding a SUDDEN elevation in an ESR when the inflammatory disease is in aggressive treatment with Rituxan infusions, the disease is NOT showing a corresponding increase in blood markers, and the ESR has previously been zero (ESR - 0) for more than a year.

ESR Labs: 07/22 through 09/01/22 - "0"

September 20, 2022 - 4; October 15, 2022 - 65;

November 29, 2022 - 93 markedly elevated ("markedly elevated" is the comment from the lab report)

Has anyone experienced a SUDDEN elevation in their ESR or can refer me to a website for more information?

Thank you.