I have limited systemic sclerosis and pulmonary hypertension. I have been having gastric problems for some time and my PPI has been doubled to 40mg twice a day. My Town Hall was offering a service of osteoporosis screening at the price of £22, which I thought was quite reasonable and went along. I am sorry I bothered. It now seems that I am at risk of osteoporosis. I am going for a DEXA scan in the next three weeks and I did hear that it may be the PPI that may be the cause. Has anyone else come across this?