Nonrandomized trial comparing MRI-guided focused ultrasound vs EBRT (external beam radiation therapy) for improved pain and QoL (quality of life) for patients with painful bone metastases.
“On the basis of the evidence provided in our study, MRI-guided focused ultrasound may represent a valid alternative for specific anatomic sites (pelvis, sternum, and long bones, including the ribs)," De Maio and colleagues wrote. "However, in consideration of the inherent bias of a nonrandomized study and the potential unmeasured variables that can account for the apparent treatment effect, our conclusions point to the need for a randomized trial to further investigate such results.” Dr. Alessandro De Maio et al, Univ of Rome.
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Accompanying editorial: pubs.rsna.org/doi/10.1148/r...