My blood smear said reactive lymphocytes present what does that mean? It was 8% on the report.
I did have a sinus infection.. can that be it? Last test in May was 7%. Does anyone know?
The blood smear has been reviewed and the differential is confirmed. Reactive lymphocytes present.
Thank you in advance for any information.
Hello--Did you find information about "reactive lymphocytes"? Here is a Wikipedia link. originalText The lymphocytes become larger as a result of antigen stimulation. Note it also says could be caused by some drugs reactions. Often these "shifts" in cell morphology reflect something--but it is usually not a sign of anything serious. For example when we get viral infections more lymphocytes are produced and the differential will show fewer neutrophils. I am a retired clinical lab scientist/medical technologist. I never worked in hematology--but always found the identification of the blood and bone marrow cells fascinating! In school we could figure out the hematologic disease by studying the blood and bone marrow slides under the microscope. We used to call these cells "Downey cells"--after the man who discovered them. Note in article. You'd have to google normal lymphocytes to see the difference in morphology between the two. Ask your MD's--even tho they might not know the reason for their presence either. Might need a hematologist! Have they appeared on all your CBC results? Even before drugs, etc.? Best to you! Kay
Thank you so much. Prior to having cancer I have not had this blood test before. So I guess it’s hard to tell. I appreciate your response. Thank you 😊
I meant the CBC blood test--which is Complete Blood Count. The counts of the white cells will come under "differential" and will show the % and/or numbers of the various white cells. In this count they would mention if they saw any unusual cells--like the reactive lymphocytes. We usually have CBC's run many times in our lives--every time we go for a medical problem! Most likely your differentials never showed these before cancer. Best! Kay
I notice a change over the months on Ibrance And Letrozole
September 2021 pre-diagnosisWBC
Your Value
6.3 10ˆ3/µL
Standard Range
3.6 - 10.2 10ˆ3/µL
RBC
Your Value
4.10 10ˆ6/µL
Standard Range
(Based on documented legal sex) 4.10-5.30 10ˆ6/µL
HGB
Your Value
12.5 g/dL
Standard Range
(Based on documented legal sex) 11.9-15.8 g/dL
HCT
Your Value
38.1 %
Standard Range
(Based on documented legal sex) 37.4-48.3 %
MCV
Your Value
94.0 fL
Standard Range
82.0 - 99.0 fL
MCH
Your Value
31.0 pg
Standard Range
27.0 - 33.0 pg
MCHC
Your Value
33.0 g/dL
Standard Range
32.0 - 36.0 g/dL
RDW
Your Value
13.0 %
Standard Range
11.0 - 15.0 %
PLT
Your Value
286 10ˆ3/µL
Standard Range
150 - 450 10ˆ3/µL
MPV
Your Value
10.4 fL
Standard Range
9.8 - 12.7 fL
NRBC's
Your Value
0.00 %
Standard Range
0 %
Absolute NRBCs
Your Value
0.0 10ˆ3/µL
Standard Range
0 10ˆ3/µL
Neutrophils
Your Value
50.0 %
Standard Range
37.0 - 72.0 %
Lymphocytes
Your Value
37.0 %
Standard Range
16.0 - 48.0 %
Monocytes
Your Value
11.0 %
Standard Range
4.0 - 14.0 %
Eosinophils
Your Value
2.0 %
Standard Range
0.0 - 9.0 %
Basophils
Your Value
0.0 %
Standard Range
0.0 - 2.0 %
Immature Granulocytes
Your Value
0.0 %
Standard Range
No defined reference range %
Absolute Neutrophils
Your Value
3.2 10ˆ3/µL
Standard Range
1.1 - 6.0 10ˆ3/µL
Absolute Lymphocytes
Your Value
2.3 10ˆ3/µL
Standard Range
0.7 - 3.4 10ˆ3/µL
Absolute Monocytes
Your Value
0.7 10ˆ3/µL
Standard Range
0.3 - 1.0 10ˆ3/µL
Absolute Eosinophils
Your Value
0.1 10ˆ3/µL
Standard Range
0.0 - 0.6 10ˆ3/µL
Absolute Basophils
Your Value
0.0 10ˆ3/µL
Standard Range
0.0 - 0.1 10ˆ3/µL
Absolute Immature Granulocytes
Your Value
0.00 10ˆ3/µL
Standard Range
0.00 - 0.10 10ˆ3/µL
February 2022
WBC
Your Value
8.0 10ˆ3/µL
Standard Range
3.6 - 10.2 10ˆ3/µL
RBC
Your Value
4.90 10ˆ6/µL
Standard Range
(Based on documented legal sex) 4.10-5.30 10ˆ6/µL
HGB
Your Value
15.2 g/dL
Standard Range
(Based on documented legal sex) 11.9-15.8 g/dL
HCT
Your Value
46.7 %
Standard Range
(Based on documented legal sex) 37.4-48.3 %
MCV
Your Value
96.0 fL
Standard Range
82.0 - 99.0 fL
MCH
Your Value
31.0 pg
Standard Range
27.0 - 33.0 pg
MCHC
Your Value
33.0 g/dL
Standard Range
32.0 - 36.0 g/dL
RDW
Your Value
14.0 %
Standard Range
11.0 - 15.0 %
PLT
Your Value
355 10ˆ3/µL
Standard Range
150 - 450 10ˆ3/µL
MPV
Your Value
10.6 fL
Standard Range
9.8 - 12.7 fL
NRBC's
Your Value
0.00 %
Standard Range
0 %
Absolute NRBCs
Your Value
0.0 10ˆ3/µL
Standard Range
0 10ˆ3/µL
Neutrophils
Your Value
63.0 %
Standard Range
37.0 - 72.0 %
Lymphocytes
Your Value
27.0 %
Standard Range
16.0 - 48.0 %
Monocytes
Your Value
8.0 %
Standard Range
4.0 - 14.0 %
Eosinophils
Your Value
1.0 %
Standard Range
0.0 - 9.0 %
Basophils
Your Value
1.0 %
Standard Range
0.0 - 2.0 %
Immature Granulocytes
Your Value
0.0 %
Standard Range
No defined reference range %
Absolute Neutrophils
Your Value
5.1 10ˆ3/µL
Standard Range
1.1 - 6.0 10ˆ3/µL
Absolute Lymphocytes
Your Value
2.2 10ˆ3/µL
Standard Range
0.7 - 3.4 10ˆ3/µL
Absolute Monocytes
Your Value
0.6 10ˆ3/µL
Standard Range
0.3 - 1.0 10ˆ3/µL
Absolute Eosinophils
Your Value
0.1 10ˆ3/µL
Standard Range
0.0 - 0.6 10ˆ3/µL
Absolute Basophils
Your Value
0.0 10ˆ3/µL
Standard Range
0.0 - 0.1 10ˆ3/µL
Absolute Immature Granulocytes
Your Value
0.00 10ˆ3/µL
Standard Range
0.00 - 0.10 10ˆ3/µL
General Information
Ordered by Alan Wing-Lun Wan
Collected on 02/03/2022 1:25 PM from Venous (Blood)
JUNE2022
5 months on Ibrance- Letrozole
WBC
Your Value
4.2 10ˆ3/µL
Standard Range
3.6 - 10.2 10ˆ3/µL
RBC
Your Value
3.40 10ˆ6/µL
Standard Range
(Based on documented legal sex) 4.10-5.30 10ˆ6/µL
HGB
Your Value
12.3 g/dL
Standard Range
(Based on documented legal sex) 11.9-15.8 g/dL
HCT
Your Value
36.1 %
Standard Range
(Based on documented legal sex) 37.4-48.3 %
MCV
Your Value
107.0 fL
Standard Range
82.0 - 99.0 fL
MCH
Your Value
36.0 pg
Standard Range
27.0 - 33.0 pg
MCHC
Your Value
34.0 g/dL
Standard Range
32.0 - 36.0 g/dL
RDW
Your Value
15.0 %
Standard Range
11.0 - 15.0 %
PLT
Your Value
279 10ˆ3/µL
Standard Range
150 - 450 10ˆ3/µL
MPV
Your Value
9.9 fL
Standard Range
9.8 - 12.7 fL
NRBC's
Your Value
0.00 %
Standard Range
0 %
Absolute NRBCs
Your Value
0.0 10ˆ3/µL
Standard Range
0 10ˆ3/µL
Neutrophils
Your Value
41.0 %
Standard Range
37.0 - 72.0 %
Lymphocytes
Your Value
46.0 %
Standard Range
16.0 - 48.0 %
Monocytes
Your Value
10.0 %
Standard Range
4.0 - 14.0 %
Eosinophils
Your Value
1.0 %
Standard Range
0.0 - 9.0 %
Basophils
Your Value
2.0 %
Standard Range
0.0 - 2.0 %
Immature Granulocytes
Your Value
0.0 %
Standard Range
No defined reference range %
Absolute Neutrophils
Your Value
1.7 10ˆ3/µL
Standard Range
1.1 - 6.0 10ˆ3/µL
Absolute Lymphocytes
Your Value
1.9 10ˆ3/µL
Standard Range
0.7 - 3.4 10ˆ3/µL
Absolute Monocytes
Your Value
0.4 10ˆ3/µL
Standard Range
0.3 - 1.0 10ˆ3/µL
Absolute Eosinophils
Your Value
0.1 10ˆ3/µL
Standard Range
0.0 - 0.6 10ˆ3/µL
Absolute Basophils
Your Value
0.1 10ˆ3/µL
Standard Range
0.0 - 0.1 10ˆ3/µL
Absolute Immature Granulocytes
Your Value
0.00 10ˆ3/µL
Standard Range
0.00 - 0.10 10ˆ3/µL
Hello DD--I am so sorry--I forgot to say (very foggy brain today!) that maybe having "reactive lymphocytes" was something you might have under normal conditions--that is why I asked if you had them on previous results. AND I did not realize they are counting them in a separate test--in my experience they would have been seen in a CBC. So sorry. Like Maddy sez--it means "something is going on" that is calling the lymphocytes into action! Reviewing your CBC results, your lymphocytes are quite a big higher in the June 2022 results. As you say, could be from a sinus infection. We probably get the same reaction after an immunization, etc. Some meds might cause it. If the "rx lmc" test was ordered separately, then your MD is looking for something in particular, so you could ask. Best! Kay
Thank you.. good to know. I put an email out to them in my chart. Thanks much for your help!!
I actually worked in Hematology labs my whole career, so I have observed many reactive and atypical lymphs in my life. Generally, we thought of them as being present when "something was going on" in the body, particularly viral.Lady Katarina gave excellent information. I would add a couple of websites for you, LabCE.com. and ScientificDirect.com. I Googled reactive lymphs vs. atypical lymphs and quite a bit of info came up.
Good Luck, hope this helps.
Maddy
It does I’m wondering if it’s the meds I’m on.
Thanks Maddy for popping in here! I have not been in a clinical hematology lab for a very long time. Ended my career in research at small companies making immunodiagnostic products! I'll make a note of your website references too. Kay
Does fatigue get better the longer your on ibrance
What time to take meds?
What happens after NED?
What to discuss with your oncologist?
Does Fulvestrant Helps my moms MBC?
