A week on from starting new treatment of kadcyla (TDM1)...

Hello, how are we all? Last week I had the first infusion of my second line treatment following scans last month which showed brain involvement and slight progression in the liver. The infusion took 90 minutes with it being the first one and then I had to be monitored for 90 minutes afterwards in case of an adverse reaction (all was well).

I was sent away with anti nausea tablets which I haven't needed so far, apparently this is a common SE of kadcyla. I have had a headache on a morning as soon as I have woken up but it goes away with paracetamol, didn't have one this morning though. I've also had constipation in the last week, so they are my 2 main bothersome SEs, apart from that I'm getting on quite well. Energy levels good, haven't had fatigue, sleeping well on a night.

Apparently I will be scanned again in around 6 weeks, CT of abdomen/thorax and a brain MRI to see if the kadcyla has had any effect on the brain lesions of which there are many.

Take care Caroline xx

[stardust1965]

Caroline, thank you for letting us know how you are doing. You sound like you are calm, accepting and doing well. I wish you all the best on kadcyla and that you get good results in six weeks time.It is also very useful to know what treatments are offered via the NHS going forward. There is never any time to discuss this subject in my oncology appointment every three months. And in a way I don’t want to tempt fate, nor do I like to ask Dr Google. So thank you for sharing here. Vicki

[Teddielottie]

Glad the change of treatment is tolerable so far and I wish you good results in a couple of months time . Take care! x

[Justme153]

Hope you get great results in 6 weeks!! I'm glad you seem to be tolerating the treatment well. Take care and keep us posted on your scan results if you feel like it . Thanks for sharing your journey!

[Hidden]

Hi CarolineI have been thinking of you, and very pleased to hear you are doing so well this week. I hope those SE’s keep manageable over the next 5 weeks, and you get some amazing results at the end of it

Clare

[Rhwright12]

Hi! I just had Radiation with the addition of Kadcyla. It worked! I was on Perjeta/Herceptin for about 4 1/2 years before progression to brain in November...Hopefully this treatment line will last a long time for both of us....😀

[Andersl]

I've been on kadcyla for a year. Very few side effects - less energy. I've found it quite tolerable. I am stage iv - though the treatment has seen a significant response. It does pass the blood brain barrier. I had radiotherapy to the brain a year ago though i believe the kadcyla has also played its part.

I've had no hair loss.

I wish you well on your journey xx