I am finishing up week 2 of my first cycle on the Ibrance 125mg / Letrozole combo. The further I get in to this the more I have been experiencing extreme bloating (to the point where my stomach is so extended I look about 4-6 mos preggers). Granted I am not a small woman but I have dropped at least 16 lbs since July. Not sure if the bloating is due to the meds or the fact that the MBC surfaced in 2 lymph Nodes within my body (one in my neck on the left and the other near my stomach). Was just wondering if anyone else has experienced bloating like this? Its very uncomfortable. I've tried heat, ginger tea, taking "Gas-X" (and I'm sure I am forgetting other things I've tried) and walking as much as I can but the discomfort remains. Any suggestions from my new community of friends?