I'm a 24 year survivor with 17 years at Stage 4 and still going strong! The cancer went into my bones in 2000 and in my chest wall and liver in 2007. I was on hormonals until 2007 and then switched to chemo. I have been on a new chemo about every year and 1/2 on average. I did Proton Therapy on my liver spot 17 months ago and that worked well. I am on Neratinib now and am getting ready for a trip to Silver Springs, MD to testify to the FDA on behalf Neratinib. I am SO excited! My quality of life is wonderful. I take one day at a time and never lose hope!