I am on ropinirole which helps me sleep, but does not cure the rls in the evenings.
I have tried to compile a list of things I know and what helps so far!!
Thinking about RLS in the evening seems to bring it on!
Iron levels - mine are always a bit dodgy anyway, but rls is much worse when I an due on or menstruating.
I have noticed that if I get stung by nettles during the day my rls is much worse in the evening. I have googled contents of nettles which are - acetylcholine (a transmitter in the central nervous system); histamine; serotonin (helps you feel well/happy); moroidon - the stinging sensation; leukotrienes - trigger contractions (usually in the trachea - related to asthma); and 'possibly' formic acid (corrosive to the skin and optic nerve in high doses)
...are there any scientist out there who can help?
Lying on tummy!
And according to wikipedia, having an orgasm!
Be interested to know your thoughts?!