More on Berberine

[DicCarlson]

So, I haven't had any RLS in many years - until the last 2 nights! Mostly my severe RLS was settled years ago with iron supplements (ferrous bisglycinate chelate). I have been taking berberine to help with cholesterol support - in the morning (500mg). I recently had my cholesterol checked and decided to move the berberine to the evening (the body produces cholesterol at night). Big mistake! I had some RLS symptoms - not severe at all, but it was there. So, researching berberine it does interfere with iron absorption and I surmise this is the cause. Yesterday, I took the berberine in the morning (as I have for a year or more) and the RLS was there again, but much, much less and dissipated in a few hours. Today I have not taken it at all - we'll see.

There are many posts on Reddit with users experiencing RLS from Berberine supplementation. These are old but never the less...

reddit.com/r/TheLongLived/c...

Older HU thread here...

healthunlocked.com/rlsuk/po...

[WideBody]

Very interesting. I have cholesterol issues as well. I have not tried Berberine although my wife takes it. Thanks for the post.

[Clamire]

Dic, did it lower your cholesterol? I guess berberine is one of those substances we with RLS can successfully take early in the day, but not at night. It may interfere with iron levels or it may interfere with transmission of dopamine

[DicCarlson in reply to Clamire]

Not really - at least I can't tell if Berberine is helping. My cholesterol is not all that high and I'm banking on the triglycerides/HDL being low as the more important metric.

[SueJohnson]

That is interesting!

[amrob123]

Thanks for sharing your experience. I was considering berberine to help with SIBO, but am now seriously rethinking it!