5-HTP anyone?: Is anyone taking 5-HTP... - Restless Legs Syn...

Restless Legs Syndrome

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5-HTP anyone?

Whippetmama profile image
5 Replies

Is anyone taking 5-HTP? I read something recently (I wish that I could remember where) that referred to a study that concluded 5-HTP was beneficial in treating RLS. I looked in the archives, but everything about it was old. Wonder if there's been any new developments?

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Whippetmama
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DesertOasis profile image
DesertOasis

5HTP “should” make your symptoms of RLS worse an hour after ingesting it (and several hours thereafter) because it raises serotonin and blocks dopamine. In the long run, it should theoretically up-regulate your receptors and improve your RLS. Here’s a quote:

“According to some research , taking 5-HTP may increase serotonin but deplete or reduce the amounts of other neurotransmitters. These include dopamine and norepinephrine. This side effect could actually make some medical conditions worse.”

Allyp69 profile image
Allyp69

I was taking 5HTP occasionally for sleep problems...made no difference to RLS and didn't help my sleep!

Jumpey profile image
Jumpey

I have usedit with no effect on my RLS. It has helped with sleep.

Birdland profile image
Birdland

It makes my RLS worse.

JennyHJ profile image
JennyHJ

this interacted with my other drugs - tramadol and pregablin and I honestly thought I was going to die. I couldn’t get out of bed for 2 days, I had a really horrible falling sensation, even though I was lay down. Plus horrendous vertigo. Doctor was not impressed I had took it on top of current medication. Sounded even worse when I said I had got it off internet

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