hydroxyzine hydrochloride antihistamine ??? Is this safe please

[Zenawarrior73]

hi

I occasionally have to take hydroxyzine hydrochloride a prescription strength antihistamine for intersistial cystitis (non bacterial but inflammatory) when I’m in a flare

I had a colonoscopy last week as a scan showed some inflammation and thickening in my descending colon they ended up removing several polyps however the bowel cleansing stuff I took has aggravated my bladder to the point im in agony and I’m going to have to take my hydroxyzine but wondered if this will massively exacerbate my already out of control restless legs

By way of an update I’m taking Topamax and Diazepam at night now for the constant muscle twitching I also have on top of the restless legs that’s still being investigated by neurology and rheumatology and I’m actually sleeping again which is good news

thanks so much to anyone who responds I think you all are flipping fabulous in this community

Xx

[SueJohnson]

Unfortunately it is a sedating antihistamine and makes RLS worse for most. Clarinex is a prescription one that is safe.

[Zenawarrior73 in reply to SueJohnson]

Thanks Sue

Appreciate the speedy response I will have to see if it works for the IC as not many anti histamines do fingers crossed I will try the GP tomorrow

[Joolsg]

Sadly it's a bad one for RLS.Have you tried mirabegrin or solifenacin for the interstitial cystitis?

I have found pregabalin also helps calms down my MS bladder spasms and also buscopan, which is an IBS med. Anecdotal reports show it can help spasms in the bladder, as well as the bowel.

And, my trusty stalwart, medical cannabis can help as well.

[Zenawarrior73 in reply to Joolsg]

Hi Jools no not tried either of those

Going to go and get buscopan from boots tomorrow as can easily get that and try to talk to gp about a different medication I’m back to see rheumatologist next week

I ended up taking a hydroxyzine as was in so much pain earlier and restless legs symptoms in my arms are crazy bad my arms feel like I’ve got bubbles exploding in them so absolutely it’s not a great med

It’s so unfortunate as it’s always worked so well to calm down my aggravated bladder 😬

Thanks for the other suggestions though

My GP is loving me right now 🫣

[Joolsg in reply to Zenawarrior73]

I can imagine! My neuro-urologist is pretty good and makes lots of suggestions to help bladder spasms and listens when I tell him what has helped.Try a non sedating anti histamine like loratedine or cetirizine as well.

[Zenawarrior73 in reply to Joolsg]

Thanks Jools you are a super star

[David7]

I take it with no added RLS problems. Helps with sleep and itching. Try it and see how it goes All the Best.

David7

[Zenawarrior73 in reply to David7]

Thanks David I ended up taking one as it was so bad