the 2 p,s park & restless

[auldreekie18]

Hi ,Pals got Restless legs and Parkinson not a good combination , taking 4 100/25mg daily Madapor and 1 mg Clonazepam also also 0.088mg Pramipexole been of and on it before I know you get augmentation but other things do not work this helps I take the Clonazepam soon as I go to bed as it makes me very dizzy and stagger but okay when in bed knocks me out for 5/6 hrs can manage during the day with exercise and on my walker will be 85 yrs next month hopefully not long to go and all this will stop ,Ithink of you all in my prayers and hope they will find a cure for this horrible condition ,try anything to help I have dont give up keep strong God bless you all ,listen to all the great advice on here and be lucky to find a good doctor ,you are not alone only to those who do not have it ,I manage it 70% of the time and have my good days and bad days and that is enough.

God bless you all never underestimate the power of faith .

So long for now

Auld Reekie.

[David1920]

Does anyone in the group know how common Parkinson’s is in RLS? In other words is this a chance association or are they linked / associated? Thanks

[SueJohnson in reply to David1920]

Https://rls-uk.org/faqs says "Most people with Restless Legs Syndrome have the "idiopathic" form - meaning there's no known cause. Consequently, there is currently no known risk of RLS progressing to more serious conditions, such as Parkinson's disease."

[David1920 in reply to SueJohnson]

Thanks Sue.

Just wondered as they are both dopamine dependent, occur in the basal ganglia and have a genetic basis, is there a known risk of coexistence? Yes, my phraseology of RLS progressing to Parkinson’s is poor use of English.

[SueJohnson in reply to David1920]

Parkinson's certainly have a genetic component but only some RLS has a genetic component. I am one of them. But they are different genes.