I had been taking Temgesic 700 mcg daily for a few months after buprenorphine patches. At this level I still had breakthrough RL and also a very dry mouth, hoarseness and some difficulty swallowing dry food. Prof. Walker had suggested that I go back on oxycodone which I had taken for two years - changing to buprenorphine patches in June 2020. I had suffered severe depression and anxiety whilst on buprenorphine and always felt it was to blame. I have now made a complete changeover to Longtec and now take 20 mg. in the day (10 mg at bedtime and the other two 5 mg doses through the day). Incidentally my anxiety and depression have lifted a lot with the change.

I am still suffering very dry mouth as other medications I have to take also cause this tendency.

I attended an ENT specialist who passed a tube into my nose and throat as far as my vocal cords and everything was OK. He thought my problem was due to GERD and suggested famotidine.

My GP sent a prescription for famotidine which I have not started yet (the side effects which others suffer seem horrendous). Then to-day out of the blue my GP sent Lanzoprazole - a PPI - with instructions to take one daily first thing in the morning. I was not told to exchange this for the famotidine so I assume this is an error on the part of the GP practice.

My question here is how do others get on with Lanzoprazole in connection with their restless legs. Is there a PPI which is better for restless legs? I do not want to take any more tablets but because of the difficulty swallowing I shall probably have to start something. I am treating the dry mouth with all the usual aids which of course only work very short term.

I would be glad if advice regarding the above medicines in their relationship to worsening RLS.

With thanks