I had been taking Temgesic 700 mcg daily for a few months after buprenorphine patches. At this level I still had breakthrough RL and also a very dry mouth, hoarseness and some difficulty swallowing dry food. Prof. Walker had suggested that I go back on oxycodone which I had taken for two years - changing to buprenorphine patches in June 2020. I had suffered severe depression and anxiety whilst on buprenorphine and always felt it was to blame. I have now made a complete changeover to Longtec and now take 20 mg. in the day (10 mg at bedtime and the other two 5 mg doses through the day). Incidentally my anxiety and depression have lifted a lot with the change.
I am still suffering very dry mouth as other medications I have to take also cause this tendency.
I attended an ENT specialist who passed a tube into my nose and throat as far as my vocal cords and everything was OK. He thought my problem was due to GERD and suggested famotidine.
My GP sent a prescription for famotidine which I have not started yet (the side effects which others suffer seem horrendous). Then to-day out of the blue my GP sent Lanzoprazole - a PPI - with instructions to take one daily first thing in the morning. I was not told to exchange this for the famotidine so I assume this is an error on the part of the GP practice.
My question here is how do others get on with Lanzoprazole in connection with their restless legs. Is there a PPI which is better for restless legs? I do not want to take any more tablets but because of the difficulty swallowing I shall probably have to start something. I am treating the dry mouth with all the usual aids which of course only work very short term.
I would be glad if advice regarding the above medicines in their relationship to worsening RLS.
With thanks
Written by
Jelbea
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Famotidine makes RLS worse for most people. Lansoprazole will interfere with the absorption of iron, but for most people will be OK for RLS. All of the PPI's will be the same for RLS.
It seems that the ENT specialist is 'guessing' that your dry mouth and hoarseness is caused by GERD. He couldn't find any issues.As you know, both famotidine and lansoprazole can worsen RLS for many people.
And they may not reduce the dry mouth and voice hoarseness.
I suppose you could try it for a week to see if it improves the hoarseness and also if it triggers RLS.
If the ENT specialist suspects acid or stomach issues, an easier solution may be to try Symprove probiotics as that can really help acid stomach and reflux and it definitely will not worsen RLS.
Hi Joolsg - I think it was a guess and I do not know if it was right. I had a hiatal hernia diagnosed over 50 years ago and have had some heartburn issues over the years, but nothing that an antacid did not take care of. I might try your suggestion of Symprove as I do not want to start any more tablets. I have an app with my GP next Wednesday so I shall discuss this with her. The swallowing difficulty is annoying. It is not too bad especially if I drink at the same time or the food is moist. Another explanation could be that the opioid is causing slowing of the swallowing process as it also slows the rest of the gastrointestinal tract.
Yes that is a side effect of opioids. It's so upsetting that the only drugs left to us cause other side effects.I noticed I was getting terrible heartburn with Buprenorphine so I started Symprove 4 months ago. Touch wood, I haven't had heartburn since.
I have IBSD, along with RLS. I take hydrocodone for the RLS, and it has never affected my bowel movements. There are days when I WISH it would slow them down, but nope. So, it's NOT a side effect for everyone.
Hi, I don’t have a response for that but I would like to assure you that I have the very same issues with Buprenorphine. I became so deeply tired and depressed just before Christmas, I had to ask for an emergency change over to something else. Unfortunately it’s not working well but I’ve managed to get down to 200 mcg which at least helps me get through until I see my doctor. I also suffered from acid reflux. I’m guessing this might even go away by itself once you’re off Bup.
I too am prescribed Oxycodone for my RLS, it’s been a godsend, but you will probably need to take stool softeners, or Magnesium Citrate to avoid constipation. Also, a good remedy for Gerd is raising the head of your bed six inches, and avoiding foods before bedtime that aggravate heartburn. .
my partner has respiratory reflux and has found fabulous help and support on a facebook site called Strictly LPR /silent reflux support group. Swallowing difficulties and dry mouth are classic symptoms of silent reflux along with chronic cough, burning mouth and throat, ear pressure, shortness of breath. When the GERD affects the respiratory system, these symptoms are common. These sites are full of people who know loads. The best authority is Dr Jamie Kaufman. Blog and website. Good luck. You are not alone.
Hi Jukebox 55 - It is so good of you to contact me with all these details and I am looking into this at present. It has been hard to get help with this and I am grateful for your post.
good luck. It is such a hard thing to deal with and with bloody restless legs as well. At least me snd my partner share the problems! The RLS site has helped me so much, delighted to return the favour. Les
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medication
UK RLS sufferers this is for you.
Changing opiods
Oxycodone 
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