I have suffered with RLS for several decades. In desperation eight months ago I began a regimine that really works well for me.
I take 4mgs of Astaxanthin and 50 mgs of pycnoginol at lunch and another 50 mgs at dinner time. In addition, I also take 250 mgs of ashwaghanda at bedtime. This has reduced my symptoms dramatically. Some evenings I can sleep through the night and other nights the symptoms are mild but not bad enough to wake me up completely after which I go back to sleep. I would also point out that there are virtually no side effects except for the calming provided by the ashwaghanda. The pycnoginol also will reduce blood pressure as it is s good vasodilater. It has been 8 months now with consistent results.