For cutting down my use of pramipexole,, I'm not sure what route to follow - cannabis, gabapentin & tramadol, methadone etc., etc. but I now know that I have to do something to get off it, yet there are so many things to consider.
I first got to EARLS by searching for info. on Iron, since my GP had just sent me for blood tests to determine my ferritin levels. I knew there was something I had seen by Dr. Earley from Johns Hopkins about some difficulties with its absorption in the brain, and how the tests needed to be done and interpreted, but I was having difficulty telling her about it. In any case, I think the test was irrelevant, in that I had unwittingly gone in to have it in the afternoon after eating, and also, they were just the basic blood tests.
But, as has been the case regularly since then, I transitioned to other posts about other aspects of RLS and happened upon one saying "Pramipexole is the key...". As I read the comments, I began reeling in horror and dismay, as I realized the severity of my situation. The comment "Are you sure this is not a typo?" by Joolsg in relation a the dosage of 1 mg. (when I, at that point, was taking 1.5 mg.!) and then further along, that it was worse than getting off crystal meth made quite an impression! While I am now down to 1 mg. (following Sue Johnson's advice to go down by .125 mg. for 2 weeks at each step) I realize that probably, the worst is yet to come. As I contemplate taking the next step down to .75 mg. today, I'm seeking advice as to whether I should do it anyway, or wait until I feel more comfortably stabilized at 1 mg.? I don’t want to fail this time, as I have in several previous attempts which were less well structured and well thought out.