Unfortunately, I my RLS has led to me getting severe depression due to lack of sleep over these past few months. I have become angry, irritated with my wife and family members causing upset with them, guilt, anxiety etc. The list at the moment is endless which isn't nice for me or my family but I have taken steps again in mending myself and I know it won't last forever.
Anyway, the link above is for an hour long seminar from USA which gives you some amazing insight into how rls effects us all.