Pramipexole and anxiety : I’m quite... - Restless Legs Syn...

Restless Legs Syndrome

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Pramipexole and anxiety

Yakester profile image
7 Replies

I’m quite sure that I have augmentation with my pramipexole. One thing I have noticed is increased anxiety. I’ve been on 0.25 x 3 in late afternoon for several years. I don’t even know what it feels like to be off the med. I use hydrocodone for backup. I think I could get by with just that after I get off the pramipexole. Any thoughts?

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Yakester profile image
Yakester
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7 Replies

If your RLS symptoms seem worse, coming earlier in the day, maybe having symptoms in your arms and/or torso or other parts of your body you didnt have before taking Pramipexole then that is augmentation. Your dosage is a bit high for the Pramipexole,, so could very well be augmentation. Look at what others have done/do when getting of a dopamine med. i cant say if the Hydrocodone will be enough, i cant advise you on that. Here in the UK its not available to be used.

Yakester profile image
Yakester in reply to

Thanks so much for your input. Have you heard if anxiety being a side effect?

in reply to Yakester

The anxiety might be because you are anxious that you might be having augmentation, not sure anxiety is a side effect of augmentation,

Madlegs1 profile image
Madlegs1

Anxiety is a reported side effect of Prami.

It may be increased by the co use of opiates. Hypersexuality and gambling are also associated with it.

You are on quite a high dose for rls. You should have someone watching your back.

Good luck getting off of it-- which you will now need to do

Search augmentation and Pramipexol on this site.

SLMCP profile image
SLMCP

Is your RLS still under control ? Please speak to your GP or consultant before stopping your meds. Good luck and take care.

Yakester profile image
Yakester in reply to SLMCP

No. Rls not under control. I messaged my internist asking for referral to neurologist. I’m a mess. Last night my legs were crazy and then I got muscle cramps. I think the cramps were because I golfed in very warm weather and, even though I tried to stay hydrated, I possibly didn’t drink enough water. Anyways, my life is going great rigyniw except for this rls mess.

rsears57 profile image
rsears57

I take one and a half pills of 5 325 and they work great

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