All over body RLS and sertraline - Restless Legs Syn...

Restless Legs Syndrome

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All over body RLS and sertraline

wsjulz profile image
9 Replies

Hi all

Since starting on sertraline I have been experiencing RLS a lot worse, so I am coming off it. Does anyone know if there is a link between sertraline and RLS? I have also been taking 400mg magnesium per day (started 3 weeks ago) and it has made no difference at all.

I am wondering if it could be a nerve issue in the spine, but that would not seem to make sense as to why I get it all over my whole body.

Can anyone shed a light on any of this?

Thanks in advance :)

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wsjulz profile image
wsjulz
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9 Replies

Sertraline is an anti-depressant and most all anti-d's will make RLS worse. Hence body RLS.

Are you taking any meds for your RLS. Magnesium doesnt work for RLS for everyone, it didnt help mine.

Madlegs1 profile image
Madlegs1

Yes! If you google search "sertraline and rls" a load of reputable references will appear to confirm that sertraline (Zoloft) is an antagonist for rls.

If you come off it you may not experience immediate relief due to halflife effects and possible withdrawal effects.

As Elisse says , magnesium helps some people, but should be in the form of citrate or glycinate. Mg citrate is cheaply available in HnB. I use 200mg about 3hrs before bed and it does seem to help. Mg oxide is useless- but offered as mg by many unscrupulous manufacturers.

You would imagine that a product labelled " Natural elemental marine magnesium" would be the bees knees. Utter marketing rubbish- it is just cheap mg oxide!!!!!😠

Another form is to make up a solution of epsom salts and water ( not tap) half and half , and rub the 'oil' on your legs or arms before bed. It may sting a little bit- if very bad , just wash it off. This worked well for my daughter in third trimester of pregnancy.

Rls is very commonly exacerbated by spinal surgery- so you are correct to assume a correlation.

All the very best.

wsjulz profile image
wsjulz in reply toMadlegs1

Ah thank you. I've just checked and mine is oxide!

ircam2112 profile image
ircam2112 in reply toMadlegs1

Based on your intent, I think you are mistaken to say Zoloft is an antagonist for RLS. It is instead an agonist i.e. it increases RLS symptoms.

FLAME43 profile image
FLAME43

ITOO AM QUITE NEW, BUT I WAS TOLD TO GET OFF THE SERTALINE AS IT WAS THE WORST FOR RLS

wsjulz profile image
wsjulz

I'm off the sertraline now, and it has made it a bit better, but now trying lots of other things such as cutting down on salt, sugar, caffeine. I am also having a blood test. Just trial and error.

steverhnmn profile image
steverhnmn

Wow, same thing is happening to me, thanks for posting. RLS started all of the body, I'm a zombie at night any more.

lizza profile image
lizza

I have same thing. Going nuts

ircam2112 profile image
ircam2112

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