I have suffered many years of RLS and despite increasing dosage of pramexipole it has recently got worse in that I have spent over the past weeks with no sleep at all some nights. The problem is aggravated by the restlessness I am now getting in both shoulder areas so much so I cannot relax particularly in bed. I end up doing exercises to tire myself out to get some sleep. It has got to a point that I will go back to my GP to see what can be done.
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