I started taking Gralise 6 days ago for RLS and peripheral neuropathy. The tingling in my hands and feet seems to have gotten better thus far, but not the RLS. I was wondering if anyone else has taken this medication for RLS and how long it took for it to start working? I'm currently taking 900mg at around 7pm. I was prescribed 1800mg but was told to start at 300 and work my way up until I found a dose that worked. I haven't moved up past 900mg yet because I don't want to take more than absolutely necessary. I'm only 30, so I don't want to overdo it with the meds. I was taking clonazepam for the RLS before, and it worked quite well, but it only worked for a few hours at a time and the Dr. didn't really want me taking a benzo to manage RLS since they are addictive.