As I am typing, my legs are abouncin'. My RLS had become worse over the years. I have tried many things. Some worked some of the time; some didn't. I started out with soap under the sheet at the end of the bed. HA! Didn't work for me. I then read in a Dr. Gott's column that a RLS sufferer found that three Hawthorne Berry supplement pills worked. It did for a long time, but my doctor was not so sure of it. He preferred magnesium, which worked for a long time. My doctor checked my iron and B levels--they were good. I tried applying Apple Cider Vinegar on my legs which surprisingly helped a little--it smelled till it dried too. I learned that anti-depressants make it worse so I reluctantly gave up Lexapro. Not only do anti-depressants make RLS worse; they also make you fat by seriously increasing your cravings for carbohydrates. AND when I am miserable with RLS, I eat to try to feel better. I also had a needed sleep test--I have sleep apnea, low oxygen intake, and RLS, probably due to all the weight gain. I was put on a low dose of Ropenirole which made me sleepy and gave me relief from RLS for four hours. I started taking one pill two hours before bed and then the other right before I went to bed around 10-10:30 pm. It generally works; however, I could not take it during they day and I could not ride in a car in the afternoon for more than 40 minutes before I was a mess. I was prescribed a low dosage of Gabapentin which I took at noon or later for the day RLS. My doctor said that we would probably have to increase the dosage and he is right. I realized that when I was in the car, my butt would start hurting and the RLS would kick in. I discovered that putting an ice pack on my lower back helped the discomfort and the RLS considerably. (That means inflammation and anti-inflamatory medication has helped until the tummy started hurting.) Another woman with the very same conditions as these changed the name from RLS to RBS (Restless Butt Syndrome) because, for us, they were usually together. That is pretty much my RLS history. I was doing great until I caught a cold. Although the cold is gone, I have not been able to return to the same satisfactory management of this frustrating condition. Like you, I am continually researching and looking for solutions. That is the main reason, I posed on the blog.