amitriptyline tablets what do people think ! - PSP Association

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amitriptyline tablets what do people think !

highhopes profile image
8 Replies

My wife who has PSP ,now been on Amitriptyline tablets 50mg.

They are now thinking to put her upto 75mg

well at the moment i cannot see them helping her.

Does anyone else have experience with this drug and the side effects ?

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highhopes profile image
highhopes
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8 Replies
jillannf6 profile image
jillannf6

hi i understand it is an antidepressant use dand toleratd well with PSP patients

i hav ePSP but am on a quite different anti depressnat

you need 2 check ht edose with your consultant ..

sosrry i cannot be of more help

lol jiLL

:-)

Jane2212 profile image
Jane2212

My mom was put on Amitriptine - can't remember the dose - but she hated it. She said she didn't feel any better and in fact she felt more woozy all the time, which was the part of PSP she hated (her "muzzy" head as she called it) she said the tablets made it worse. The dr tried to increase the dose but she refused and came off it. I've heard that some patients sleep better with it and are calmer but that's the sedative effect which my mom didn't like. A friend without PSP is on 75mg of this drug and loves it but she says she's in bed by 8pm because it makes her tired.

Jane xx

Don't forget PSP itself makes you tired. My mum blamed any tablet she took for making her tired but actually none of them were causing it. Madopar worked fer her even though many don't feel the benefits and although she needed 10 tablets a day it kept her mobile right up to 6 weeks before the end. She always said it made her drowsy but she was far far worse before the Madopar.

Mum never took any antidepressants but was getting more and more tired as time went on. Eventually she would want to go to bed straight after tea and sometimes before. She went from being a 6am to midnight person to a 10am to 4pm person (with a nap thrown in at 2).

In the latter stages after Christmas she was sleeping virtually all day, even napping in the middle of meals.

marusela profile image
marusela in reply to

i agree.... :)

( hugs Dianne)

riosenior profile image
riosenior

Ring the PSPA helpline for advice

MaddyS profile image
MaddyS

My hubby itakes Amitriptilyne 10mg 1 per day for dribbling. The 10mg has no effect for depression (he, thankfully, does not suffer from that yet(?)) the side-effect of this drug is drying the mouth a little bit. It works well. He takes the table before going to be, as it does make you sleepy. Sorry do not know about the anti-depression side of it.

Good luck. Maddy

Peter3 profile image
Peter3

Hi Highhopes,

My husband is on Amitriptyline 50mgs to help relieve muscle spasm he has in his shoulder and arm which causes him a great deal of pain. He initially started on 10mgs with the dose increasing until it worked.

His only complaint is that of dry mouth, having said that he still dribbles all the time.

He isn't on Amitriptyline for depression, however, it has helped him to sleep well most nights, that has been a beneficial side effect.

Best wishes

Peter3.

Aine2 profile image
Aine2

Hi highhopes , my brother was on Amitriptyiline for about 4 years of his illness , to us it was like a miracle drug because J.J. was would get no sleep without it . What suits one person might not suit another .. Best of luck to you whatever your decision is xxxx

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