Inappropriate laughing

[gypsywoman1947]

My husband has been prescribed a small dosage of Lomizipane to curb this inappropriate laughing that he can't stop , has anyone else had any experience of this drug, a week in and it's not working yet. X

[Yvonneandgeorge]

Is it lorazepam? George has that for when he gets agitated only 1mg seems to work, for him. The inappropriate laughing George does not do that anymore, it was really bad. Yvonne xxxxx

[gypsywoman1947]

Actually I see I spelt it wrong its Olazapine and he takes 2.5 mg , I was a little worried about it but the hospice doctor prescribed it. After reading the leaflet I did wonder if it was better to put up with the laughing but he wants the laughing to stop also. I just wondered if anyone else had used it, I suppose it is a low dose. Xxx

[sammy90210 in reply to gypsywoman1947]

my dad did not have this problem per se - but please be careful about dosage anyway, there can be side effects, better to confirm with a doctor

[daddyt]

I'm not really sure that there is a medication for the inappropriate laughing... check with others who post here. I'm the opposite... have had many unexplained tearful episodes. I haven't laughed for well over three years now. If I had a choice... inappropriate or not, I'd take laughing over crying.

[gypsywoman1947 in reply to daddyt]

Yes you are right the laughing is preferable to the crying. However we have had it in a funeral, middle of meals when out and always in emergency situations at home where I have to clear up., it's constant and frustrating for him and me and he too would like it to be controlled. The neurologist states meds can help so we will see. , but yes if I have to choose then I'll take the laughing . Best wishes to you. X

[daddyt in reply to gypsywoman1947]

I can certainly see where it could be embarrassing at times. We try our best to educate family and friends to potential behaviors. It would be interesting to see what the doctor prescribes. Warmest Regards

[DenB]

My husband has only laughed inappropriately once or twice that I remember,thank goodness. He has cried a lot but as others have said, the laughing thing may be a little embarrassing but it isn't so heart wrenching.

The last time he laughed, when he probably shouldn't have, was probably a year or so ago. We were in the cinema, watching an action film, someone was dying in the movie and it was quite a poignant moment, when he just started laughing out loud!

I really don't know what anyone else watching the film thought but it ruined the moment for me!!! Ha, ha.

I do laugh to myself when I remember that but I am at the same time sad because that was, and is, the last movie that he will ever see at the cinema.......

He would go into sensory overload if he sat in a cinema now.

DenB x

[Tttp]

Hi gypsy with PSP you can have outbursts of laughing or crying it just effects individuals so different I am fortunate my brother smiles and laughs never complains even when he falls and gets hurt he will say it does'nt hurt. So are you saying your husband was prescribed Olazapine? If so I would be careful with that. It has not been approved by the food and administration also has some pretty dangerous side effects, I don't give my brother no meds like that of any kind sometimes it's better to put up with things than take something with a lot of side effects. I wish you and hubby well. Nettie

[gypsywoman1947 in reply to Tttp]

Thank you Nettie , it has been prescribed by a doctor and is the lowest dose , I was aware it's pretty potent but we see doctor again tomorrow so I'll query it all again. X

[Gracie_Girl]

Hi Gypsy,

I don't know anything about the drug you're talking about, but my sister also has inappropriate laughing and crying. Neither one is any fun. My sister's primary doctor prescribed Nuedexta for her. It is normally prescribed for those behaviors associated with Pseudobulbar Affect disorder. It hasn't completely eliminated the laughing or crying, but it has reduced them drastically. I, too, was sceptical about a drug I never heard of before, but after posting my concerns here and consulting another of her doctors, I felt this drug was as about as safe as we were going to get. I'm even thinking of asking about increasing her dosage.

Anyway,don't stop asking questions and don't stop using this forum. Good luck,

Becky and Gracie