If you have any heart related issues, my advice would be to stay away from Lupron.
Years ago I had my mitral valve in my heart replaced, which is doing good... now.
I was on Lupron with a shot every three months for 15 months. At the 15-month time, I noticed that I had a really rough time waling up stairs - to the point I was pulling myself up each stair using the hand rail.
When I received my last shot, I found out from my cardiologist that the Lupron had affected my heart. With each heart beat the blood in the heart should be pumping oxygenated blood through the heart aroun 88 percent. My heart doctor told me that my heart was only pumping 43 percent of the blood and my feet and ankles were just not recieving the oxygenated blood. Heart failure is when it would reach 41 percent.
I was taken off the Lupron and my heart returned to normal.