question

[allshallbewell]

After a year on active surveillance following an initial biopsy that showed intermediate favorable level of pc, a more recent biopsy showed all samples to be Gleason 6 (3+3).

My urologist is very supportive of continuing with active surveillance. I will have periodic psa testing and probably an annual MRI.

He seemed to think it might make sense to wait 3-4 years for another biopsy - depending on what we learn in that time frame.

Looking ahead a few years, I am uncertain if it will be wise to have another biopsy - or if I should only do so if there is a cause for increased concern from the MRIs and PSAs.

I welcome your perspectives.

Thanks!

[Tall_Allen]

Decipher?

[allshallbewell in reply to Tall_Allen]

As a recall it was 37 if I have the right test in mind … have to look at it again. I later did very thorough genetic testing through Dana Farber given family history and this showed no genetic link.

[Tall_Allen in reply to allshallbewell]

Then why not continue with AS? mpMRI every few years, and biopsies if warranted.

[allshallbewell]

Thanks. Biopsy warranted if there is a significant change in MRI and/or PSA?

[aceace12]

im similiar been on AS 6 years ...psa every 3 months

[allshallbewell in reply to aceace12]

Thank you!

[woolcotton]

my first year MRI showed changes and “concerns” Followed by a biopsy, changes were from 3+3 & 3+4(4 less than 5%) in the original diagnosis, to 6 3+3s. 4 not found. Decipher low. 6 month’s later MRI showed no changes. Suggestion is AS. Plan is for PSA in January. I might ask for another MRI to check. In NYC with MSK.

[allshallbewell in reply to woolcotton]

Thanks! Good luck!

[woolcotton in reply to allshallbewell]

You as well!!