Trying to find out whether I should be taking NMN or even niacinamide is kind of confusing. My dermatologist said I should be taking at least 500 mg of niacinamide daily because it can help lessen or prevent actinic keratoses and basal cell carcinomas, which my skin is riddled with from sun damage. I've had melanoma three times, so this is important to me -- the AKs and BCs don't progress into melanomas, as far as I know, but AKs can progress to squamous cell cancers and BCs can get pretty invasive. So I've been taking 1000 mg daily of niacinamide for a couple of years. Then I discovered (here I think) NMN -- nicotinamide mononucleotide, supposedly the whiz-bang sooper-dooper version of niacinamide that helps retard the aging process, maybe fights Parkinson's (not that I have that). So I've been taking 1000 mg of that for a few months. In all this time of taking niacinamide, I haven't really noticed much improvement in my skin, or a lessening of AKs or BCs, but they haven't gotten any worse either.
Only now do I happen on the link between NMN and NAD+ and cancer, since NAD+ seems to stimulate cancer cells (and I've had non-metastatic prostate cancer for the last 14 years) -- something to do with now NAD works to repair DNA, and cancer cells can take advantage of that just like normal cells. Someone on HU asked the other day about guys who had been diagnosed with PC and then with melanoma, which is exactly what happened to me.
OTOH, sometimes NAD+ can be curative to some extent, depending I guess on all kinds of complex interactions of body chemistry and god knows what else. The studies I (tried to) read left me kind of dangling.
So now I think I should maybe stop taking niacinamide altogether. I'm wondering what anybody's thoughts/insights are about this.
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