Liquid biopsy vs. Transperineal - Prostate Cancer N...

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Liquid biopsy vs. Transperineal

Longrunner profile image
9 Replies

Is liquid biopsy ever used as an alternative to transperineal biopsy for diagnosis and guide to follow up treatment?

I don’t want to go down a research ‘rabbit hole’ if there is current scientific consensus on its diagnostic value and treatment guidance for Prostate cancer

I already have more than enough to ask my urology oncologist before I schedule my necessary biopsy! Thanks in advance for everyone’s knowledge and experience

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Longrunner
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9 Replies
Tall_Allen profile image
Tall_Allen

Do you mean the Sentinel Prostate Test done on urine? Let us know if you can get it and what it costs.

mirscientific.com/

I haven't heard from any patients who have used it instead of a biopsy.

maley2711 profile image
maley2711 in reply toTall_Allen

MIR does not make any claim that their 4 risk categories are any more predictive of future metastasis than are the Gleason scores, correct?

Tall_Allen profile image
Tall_Allen in reply tomaley2711

The NCCN risk categories predict for recurrence. Sentinel correctly identifies the risk categories.

Longrunner profile image
Longrunner in reply toTall_Allen

🤔 Is it the case that Sentinel identifies risk categories with greater specificity and accuracy than a transperineal biopsy or is a diagnostic tool used in addition to a biopsy.?

Tall_Allen profile image
Tall_Allen in reply toLongrunner

The risk categories are defined by biopsy, so it can't be better than the definition.

Longrunner profile image
Longrunner in reply toTall_Allen

Thank you very much. I am going in the wrong direction. Your referral in another post to the NCCN Guidelines is very much appreciated. I have been fumbling around to determine and understand the next step in my diagnosis.

davenj profile image
davenj

Based on this 2018 article, more testing is still required.

ncbi.nlm.nih.gov/labs/pmc/a...

Currumpaw profile image
Currumpaw in reply todavenj

Nice davenj,

You posted what needed to be read!

I believe I came close to having this very test just before it was shut down. I knew the test was on borrowed time and if there were questions about it's accuracy I was not going to spend hundreds for suspect results.

If this type of testing can be refined it would certainly be more accurate than the biopsy needle.

The most accurate test today for prostate cancer is a pathology report on a removed prostate.

Currumpaw

Longrunner profile image
Longrunner in reply toCurrumpaw

Agreed. It’s dropped from my radar. Thanks.

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