Fenbendazole-Mebendazole (and other stuff) PSA progress report

[kapakahi]

Prior to Nov. 2018: PSA generally between 0.6 and 0.9 following my last HIFU in 2015

Nov. 2018: 0.9

mid-April 2019: 1.871

mid-May 2019: 2.277 - urologist says PC has returned; no biopsy; Axumin and MRI scans note "anomalous" activity in the midline suggesting recurrence, no metastases seen; begin fenbendazole (4 g) 3 days on 4 days off after reading Joe Tippens's blog

mid-July 2019: 1.824 - continue fenben 4g 3on/4 off

mid-August 2019: 1.505 - continue FZ 4g 3on/4 off

mid-September 2019: 1.996 (anxiety level rises) - continue FZ 4g now daily

mid- October 2019: 1.5 - reduce dosage to 1g or 2g (whatever I could get), sometimes daily, sometimes M-F, sometimes every other day (essentially 3on/4off) - used LabCorp because that's what LEF contracts with

mid-November 2019: 1.5 - Quest (by my PCP)

12/6/19: switched to mebendazole because fenben was getting expensive for an unproven medication and the sources on Amazon were sometimes not in stock - and it's pills instead of granules so much easier to take, and apparently just as effective - 11/21 ordered 750 mebendazole tablets 100 mg from India for $193.50 + $15 shipping - received 12/6 and started taking 2 pills with lunch (peanut butter = fat) and 2 with dinner (always some fat)

December 12, 2019: 1.4 LabCorp

Jan. 23, 2020: 1.1 Quest - this is what can happen when you don't use the same lab every time - Quest noted that their assay method could result in a reading up to 20% lower

Feb. 20, 2020: 1.4 LabCorp - makes me think Quest's reading was indeed an anomaly - sticking with LabCorp from now on

May 19, 2020: 1.3

July 20, 2020: 1.2 - reduced mebendazole dose to 2 100mg tablets daily (down from 4 daily) - so in 14 months PSA has dropped from 2.277 to 1.2

For the entire time taking fenben and mebendazole, my liver enzymes have remained consistently normal.

I began adding other purported cancer-fighting meds last year, so I have no real idea how much (if any) of the PSA drop is due to mebendazole and how much (if any) is due to the other agents (all of which I discovered on Health Unlocked prostate cancer forums):

DIM - 300 mg starting June 2019 but took it very intermittently until March 2020 - since then it's been daily

cimetidine - 200 mg since November 2019 to help low bioavailability of mebendazole and for its own possible anti-cancer properties (also helps with GERD)

loratadine - 10 mg - not sure when I added this - late last year I think (also helps with hay fever)

artemisinin - 100 mg - since August 2019 (interesting that artemisinin is an anti-helmintic like mebendazole; it stops cell division like mebendazole but in a different way

butyrate - 600 mg - since August 2019

[Afterglow]

Very interesting. It's obvious that the addition of Fenbendazole played a part in halting the progression of your PSA from climbing further. Odd that with so many people here looking for ways to halt and combat advancing cancer that the use of this medication is not discussed more.

[kapakahi in reply to Afterglow]

well, like I said, this is where I first read about ALL of these possibilities - it's impossible to attribute the drop in my PSA to any or even all of them, and I would never advise anyone to abandon SOC in favor of these unproven remedies, which should be used only as adjuncts if they don't interfere with proven meds - suffice it to say that this is the first time since I was diagnosed in 2008 that my PSA has declined without treatment (which was HIFU - four times!).

[treedown]

The question would be is this treating the PSA or the disease. Also have you checked what assays the different labs are using. My Quest uses a different one than my GP and states results could be 20% lower.

[kapakahi in reply to treedown]

I noted the Quest assay in my post - since I'm using LEF's service, I stick with LabCorp now. As for treating the PSA or the disease - legitimate question, but fenben and mebendazole, as well as some or all (I forget how many) of the other meds have been shown to actually kill cancer cells and/or stop them from dividing. The question for all of these meds is the quality and quantity of the studies - for now, those studies are all there is to go on. AFAIK I'm not taking anything known to merely mask PSA.

[Ramp7]

Joe has updated his web page.

Looks like you have read Jane McLelland's book.

[kapakahi in reply to Ramp7]

Thanks for the tip about JT's updates. I don't and won't do Facebook so I don't get to participate in his FB group, but I'm doing OK without it. I haven't read or even heard of Jane McLelland's book.

[Ralph1966]

Happy for your PSA results, but my question is: Did you have any new PET scan?

If this is working then the PET scan (Axumin or any other type) should show regression of the cancer, right?

I am taking Fenbindazole 3on/4off and will need to repeat my Axumin scan possibly next month.

[kapakahi in reply to Ralph1966]

No, no new Axumin or other scan since the ones in May 2019. Maybe I should ask for another one. The problem with scans for me is the scarring I have from four (4) HIFUs - kind of messes things up for scans. The leading radiologist here (Oregon) refused to give me a PSMA scan because of this - "I wouldn't know what to scan." But it could be worth trying Axumin again, if my doctor cooperates (not a given).

Joe Tippens suggests that taking fenben or meben daily is probably best as long as the liver remains healthy, but he did well with the 3 on/4 off protocol, and he was in very bad shape at the beginning. I've been lucky to have no mets despite having PC for 12 years - lucky to have started with Gleason 7 (4+3), then HIFU, and now fenben/meben and all the rest, plus of course the prostate cancer forums on HealthUnlocked, without which I would have never learned of these options.

[Tralaladeedah]

Thank you for updating. Please don't stop. I tried to get my parents, educated people, both with PhDs (not in science, though), to consider Joe Tippens story. They didn't. My mother was dead from pancreatic cancer after two years this past November. I'm no scientist either, but I don't worship the establishment. I cured my son's ringworm with $9 bottle of tea tree oil when the doctors wanted to give him expensive meds that might damage his liver. Excuse me? it would have taken six weeks, with hundreds paid in visits as well. I'm not an idiot. I don't hate doctors, but I do know that money rules the world. From there, I can make a lot of deducations. What was the best website(s) that you've found in terms of looking into alternative cures? I'm not sick, but you never know. Bless you. I'm so glad that you're well!

[Hidden in reply to Tralaladeedah]

So sorry to hear about your mother.

If you are still interested in alternatives you might like to read this PUB MED case report.

Unresectable Pancreatic Adenocarcinoma: Eight Years Later.

ncbi.nlm.nih.gov/pmc/articl...

[kapakahi]

this right here was the best website I've found in years of searching, especially the Advanced Prostate Cancer forum - but I'll bet there are other Health Unlocked sites for different issues that are also good. Information, both good and bad, has become much more available thanks to the web.

[Getz]

What is the address in India for ordering Mebendazole. I just bought 6x 100mg tablets for $16 in Australia.

[kapakahi in reply to Getz]

alldaychemist.com/mebex-100... it's $15 shipping to USA, don't know what it would be to Australia. These pandemic days it can take up to a month to arrive - India's been hit hard by covid.

BTW - it's been a year since I followed up reporting on my PSA/mebendazole experiment. Since January I've had to use Quest all the time now because the local LabCorp place closed. Quest's readings are up to 20% lower than readings by LabCorp's methods. In December my LabCorp PSA was 1.4; in January 2021 my Quest PSA was 1.1, so that 20% rule works out. But then I didn't get another test till June, and in the meantime I ran out of mebendazole - forgot to order in time, so I wasn't taking it for at least 2-3 months. My June result (Quest) was 1.5, and the 20% lower rule meant it would have been maybe 1.8 LabCorp. Which scared me somewhat. Got the mebendazole again one month ago (July 23) and started taking it again, 2/day - my August 18 Quest result was 1.3 (1.5 LabCorp). FWIW.

[Getz in reply to kapakahi]

Thanks for that. So the Mebendazole are 100mg and you take 2 each day. Shall follow your link and order.

[kapakahi in reply to Getz]

I pay by eCheck - it's easier. They used to take credit cards, but now I think there's a fee attached.

[Getz in reply to kapakahi]

Just bought 180 tabs for$93.84. eg 50c a tab instead of $2.50 Thank you.

[kapakahi in reply to Getz]

gosh that seems expensive - I pay 27¢ each - you're in Ozzieland? I didn't know there was that much difference in the value.

[Getz in reply to kapakahi]

Just found my receipt from the chemist which showed each tablet costing $2,80 so .50 cents is great. I think our dollar is about 70c US. I'm still happy. $1/day is fine. Some of my supplements for PD are far more expensive.