Latest PSA results while on mebendazole

[kapakahi]

So it dropped from 1.4 in December to 1.1 in January - but with a caveat of unknown (to me) importance. This is the first time I've noticed that different labs use different methodology to come up with their results, so I included the methods here FWIW. Quest seems to have gone from Siemens chemiluminescent to Beckman ultrasensitive, then Beckman Coulter, and back to Siemens, while LabCorp (the Life Extension Foundation lab) seems to use only Roche ECLIA. Now I don't know what to make of my results - Quest says Siemens chemiluminescent will give results 20% lower than Beckman Coulter, but how does either of those compare to Roche ECLIA? And the labs say that different methodologies cannot be used interchangeably. I mean two labs and three different methodologies? How is this rational and justifiable? It makes zero sense to me, but there must be a good reason. Right? Since LEF uses only LabCorp, I guess I should have my doctor's requisitions sent to LabCorp from now on.

Prior to Nov. 2018: generally between 0.6 and 0.9 following my last HIFU in 2015

Nov. 2018: 0.9 Quest Siemens

mid-April 2019: 1.871 uh-oh Quest Beckman Coulter

mid-May 2019: 2.277 - Quest Beckman Coulter - urologist says PC has returned; no biopsy; Axumin and MRI scans note "anomalous" activity in the midline suggesting recurrence, no metastases seen; begin fenbendazole (4 g) 3 days on 4 days off

mid-July 2019: 1.824 Quest Beckman - continue FZ 4g 3on/4 off

mid-August 2019 1.505 Quest Beckman - continue FZ 4g 3on/4 off

mid-September 2019 1.996 (anxiety level rises) - continue FZ 4g now daily

mid- October 2019 1.5 LabCorp Roche ECLIA - reduce dosage to 1g or 2g (whatever I could get), sometimes daily, sometimes M-F, sometimes every other day (essentially 3on/4off) - this is when my urologist refused to order another PSA because he said I need it only every 3 months, despite the scans showing cancer and despite my taking fenbendazole - maybe he wants to wait 3 months to see if it metastacizes?

mid-November 2019: 1.5 Quest Beckman Coulter - got my PCP to order this one

12/6/19 I switched to mebendazole because fenben was getting expensive for an unproven medication and the sources on Amazon were sometimes not in stock - and it's pills instead of granules so much easier to take, and apparently just as effective - I ordered a lot in case some lowlife pseudo-pharma company (doesn't create meds, just buys the rights to sell them) buys all the Indian rights like it has in the US. So on 11/21 ordered 750 mebendazole tablets 100 mg from India for $193.50 + $15 shipping - received 12/6 and started taking 2 pills with lunch (peanut butter = fat) and 2 with dinner (always some fat)

December 12, 2019: 1.4 LabCorp Roche ECLIA

Jan. 23, 2020: 1.1 Quest Siemens - This otherwise hopeful drop from 1.4 to 1.1 may be deceptive because of the different labs' different methodologies, I ordered another LEF LabCorp test and will post the results as soon as I get them. But at least the downward drift in PSA is continuing with mebendazole. I've read something about the anti-helmintics gradually losing their cancer-fightling powers with time, but I see Joe Tippens still seems to be going strong after 3 years, and he was far worse off than I ever was, so maybe...it's actually working?

[kapakahi]

Update 1/27/2020: The new LabCorp result is 1.4 - the same as in December. The Quest 1/23/20 result of 1.1 was an illusion: Quest says this about their method: "The test

result will be approximately 20% lower when compared to the equimolar-standardized total PSA (Beckman Coulter)." Well, LabCorp uses Roche ECLIA - is that the same as "equimolar-standardized total PSA (Beckman Coulter)"? Because the difference between the two results is indeed about 20%.

Quest is really unhelpful if you want to keep track of your PSA - for my November result they used Beckman Coulter, about which they say "The test result will be approximately 20% higher when compared to the WHO-standardized Total PSA (Siemens assay)." So what do they do on Jan. 23? They switch to the Siemens method! What's up with that? It's ridiculous on the face of it. I mean, WTH is the point of getting tested if you can't compare one test with another?

Bottom line: My PSA didn't change from December (1.4 LabCorp) to January (1.4 LabCorp). Oh - and I'm not using Quest anymore.

[nobaday]

What was company/ contact info from India for 100mg mebendazole. My friend could not find any OTC in Cabo Mexico and no one is travelling toMexico from Canada at the moment!

How u doing now?

[kapakahi in reply to nobaday]

Finally got up the nerve to go to a lab for PSA (lots of sick people go to labs, but it was OK - they take your temp and I have an N-95 mask). So my 5/19/20 PSA is 1.3, down 0.1 from 2/20/20 - continuing its steady decline.

Still taking mebendazole, same dose (200mg twice a day, with 200mg cimetidine) - I get it from alldaychemist.com/, usually takes a couple weeks but it's taking longer now since not so many flights leaving India - they've been very reliable for the 10 years or so I've been using them.

I forgot to get my liver enzymes tested this last time, but they've been normal since I started last summer with fenbendazole.

Just to confuse matters (as to what's working and what isn't), I've started taking DIM and artemisinin again after a hiatus of a couple of months or so; and sodium butyrate just in the last month. I also take metformin (1g time release twice a day), but that didn't stop the cancer from coming back - I take it for pre-diabetes.

Based on Tall Allen's info and warnings about vitamin E, the d-alpha form, I cut that way back (it's in my multi) and started with gamma E, which is supposed to counter the possibly pro-cancer effects of d-alpha.

So I'm continuing with the mebendazole and the other possible anti-cancer supplements.