Merry Christmas to all.
I think like many before me, I have reached a stage in the PMR journey were I am completely flummoxed. My PMR flared after tapering from 11 mg to 10 and then too quickly to 9.5. CRP went from normal back up to 28, along with considerable pain. Thanks to the advice I received here, I got the flare under control by going to 16 mg, and stayed there for 2 and a bit weeks while everything calmed down. A blood test a week mid-way in the protocol regime showed CRP down to 8.
I maintained the 16 mg for another 10 days then began to drop back. First step down was to 13 mg, but within 12 - 24 hours that proved disastrous as pain across the shoulders and hips started up again. The next day I went to 16 mg again and was due the next blood test the 2 days later which showed normal - the GP has been monitoring the flare closely. Still in pain (despite the low CRP) I had a physical examination by a locum on Christmas eve. That ruled out any other obvious things going wrong like slipped disc, vertebrae fracture etc. and reconfirmed that the pain was PMR. It was suggested I raise the dose again up to 18 mg then 20 mg.
After 4 days of the higher dose, the pain has largely abated from the neck and shoulders, but the lower back and girdle around hips remains the same or possibly worse. The pain improves very slowly during the day and is calmer by the evening but it's back again by morning and reaches a peak around 11.00 to 12.00.
It seems very much PMR pattern but even this much higher dose (compared to pre-flare) seems very slow to act. Has anyone experienced a similar pattern?