Supplementary question re Lansoprazole

[calibriel]

I have been very interested in the responses to the question posed by crochetgardener as I have been on Lansoprazole ever since I was diagnosed in 2020, and I organise my whole morning around taking it before my breakfast - something which I’ve got used to, and it causes me no significant inconvenience; however, I’ll be staying in a hotel for a few days at the end of the month, and it might be easier if I take up the suggestion of taking it last thing at night.

My question is, what’s the best way to shift my dosage time? Have one day when I take 2 doses - i.e. one at breakfast and one last thing at night - or should I have a couple of days where I take it later each day, i.e. one before lunch, the next before the evening meal, etc? Would there be overdose effects if I take the first option of 2 in one day - albeit about 17 hours apart? Thank you

[calibriel]

PS I should add that I normally take my - currently v low - dose of pred with my breakfast

[PMRpro Ambassador]

What dose of lansoprazole are you on?

[calibriel in reply to PMRpro]

Thanks for replying. 15mg Lansoprazole and 3mg pred almost tapered to 2.5

[PMRpro Ambassador in reply to calibriel]

For the lansoprazole - at that low dose I'd take a second dose before bed and just switch like that.

But at that dose of pred - do you NEED lansoprazole at all? But don't just stop all at once - taper it if you decide to stop the PPI.

[calibriel]

Thanks for the advice. I'd quite like to stop the lansoprazole - maybe after I've been away. I almost always have kefir and/or yogurt with my breakfast: is that likely to be enough to protect my stomach from the ill effects of the pred?

[PMRpro Ambassador in reply to calibriel]

I've never taken ANYTHING - except if I need to take ibuprofen for more than just the odd dose.