Osteocalcin and adrenaline rush

[HeronNS]

So it's not adrenalin we need, apparently, but osteocalcin!

telegraph.co.uk/science/201...

[HeronNS]

My next question: can chronic stress, such as many of us experience, cause bone thinning?

[magmapearl3 in reply to HeronNS]

Good question HeronNS .

[CT-5012]

Thank you for the link, interesting read.

[HeronNS in reply to CT-5012]

The science correspondent on our afternoon radio show was talking about this today and when I looked it up, there it was, right at the top of the google feed!

[nuigini]

Hard to believe, but who knows.

[piglette]

They ought to run a youth club for teenagers that definitely seems like an adrenalin rush, oh no it’s a sugar rush!

[Hidden]

I think this is original source heron...a bit long for me tonight but might be interesting to see how much it resembles the media version!

cell.com/cell-metabolism/fu...

[HeronNS in reply to Hidden]

As I just replied above to CT-5012 I was following up an item on the radio by our regular science correspondent. I had missed the beginning so I don't know her source but no doubt it wasn't the Telegraph! The Telegraph article seemed to be very clearly stating the same points so I went no further.

And my question - yes I found a research article which as far as I can tell does say that stress affects the bones but it was very long and scientific so I didn't bother to read it. There's really only just so much a layperson like me needs (or wants) to know!

[Hidden in reply to HeronNS]

😂😂😂 agreed. I do usually just check things have gone beyond modeling stage and are out of animal testing phase. The we know it may only be 5 or 10 years before it may have clinical trains. I read things lots of times and then it turns out it's rat or mice and it may never move forward as a bit of research.

[HeronNS in reply to Hidden]

I posted this because I thought it may have some implications for us as our adrenal responses are compromised by pred.

[Hidden in reply to HeronNS]

It may also address no pred cortisol issues caused by stress, insomnia etc. You can imagine an evolutionary role and the HPA axis being disturbed by so called natural issues that make HPA wonky. Thanks for this heron..

[PMRCanada]

Very interesting. Especially since I struggled with work-related PTSD, in which the symptoms of hyper vigilance about my safety meant I my body was often experiencing the “fight/flight” response.

[TooSore]

So then what does adrenaline do I wonder?

[scats in reply to TooSore]

Just what I was wondering, we certainly seem to need it.

[HeronNS in reply to TooSore]

yourhormones.info/hormones/...

[Rache]

This is very interesting! Thanks for posting. Yet another possible demonstration of how mind and body are one and how much our body is affected by our experiences and how we deal with stressful events.

[TooSore]

Can you help put this in perspective? I'm not sure I have things straight. When we take prednisone it stops the production of cortisol, correct? And the body needs to start/increase the production as we taper off prednisone. When it doesn't keep pace properly is when you feel fatigue, achy, and in my case weepy. How does this new information change or affect the understanding of what's happening? And does it help the doctors figure out how to help?

[HeronNS in reply to TooSore]

I find it puzzling, too. But I do wonder if the stress which pushes us towards PMR is also having an effect on our bones.