Zoledronic Acid for osteopenia: Study done in New... - PMRGCAuk

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Zoledronic Acid for osteopenia

Janicep profile image
9 Replies

Study done in New Zealand and published in New England Journal nejm.org/doi/full/10.1056/N...

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Janicep
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scats profile image
scats

Thanks for that.

I had one ZA infusion just over a year ago. I refused the second one because I had a lot of pain in the bones around my hip replacement, bone pain is one of the recognised side effects. I also had a bad taste and feel in my mouth for most of a year which I suspected may be linked to it.

Both symptems have since cleared.

I have a lot of dental work and the mention of ZA sent my dentist into panic.

Seems from this it should still be working, don't tell my dentist!

Janicep profile image
Janicep in reply to scats

I had been on the oral equivalent and was offered the infusion in early August this year. I said yes as my bone health is low in my hip area. I am lucky that I have had no side effects to my knowledge. I will be very interested in another Dexa Scan maybe in 2years and interesting that they recommended the infusion to be at 18months apart

Pongo13 profile image
Pongo13 in reply to scats

Just joined a new dental practice and was told if I need an extraction in the future it will have to be undertaken in hospital. For how long, I Asked? And then, having read on here AA stays with you for years, even after you've stopped taking it (and no one knows how long) I already guessed the answer - from now on.... Best safe than sorry I suppose.

scats profile image
scats in reply to Pongo13

Pros...hospitals don't charge.

Cons... two visits needed, one for assessing situation, one for treatment. Much longer journey and waiting.

Had extraction with no problems at all.

PMRpro profile image
PMRproAmbassador

But the figures are worth noting - this is in older patients with osteopenia and OTHER RISK FACTORS. There are a lot of things to be done to reduce the risk of fracture which have no side effects - removing hazards and avoiding risky situations (DON'T stand on chairs!!!), keeping vit D and hydration levels up, providing appropriate exercises to improve balance.

scats profile image
scats in reply to PMRpro

I did think they were rather accident prone!

Primarose profile image
Primarose in reply to scats

I'll second that scats, maybe they were hand picked. ;-)

PMRpro profile image
PMRproAmbassador in reply to Primarose

Wouldn't be the first time!!!

HeronNS profile image
HeronNS in reply to scats

The biggest risk for fracture is falling, and anyone can break a bone no matter what their DXA scan says.

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