Oh goody, more good news! : "Autoimmune Disorders... - PMRGCAuk

PMRGCAuk

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Oh goody, more good news!

75 Replies

"Autoimmune Disorders Linked to Psychosis"

psychologytoday.com/us/blog...

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"When we remember that we are all mad, the mysteries disappear and life stands explained." ~ Mark Twain

Mark Twain

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75 Replies
stellafmdm profile image
stellafmdm

Oh goodness! and I have coeliac disease as well!!! 😞

in reply to stellafmdm

Hmmmm? Oh well... just go with it, all the best people are mad!

Primarose profile image
Primarose

OMG, maybe they should put us all on "Happy Pills" then we shall be miraculously cured.

One wonders what the author was on when he wrote that load of twoddle.

Prims aka Freak 2.

in reply to Primarose

"Twoddle," what a great word! A good Rant title, don't you think!

Primarose profile image
Primarose in reply to

I made that one up but it seems to fit!!:-)

I would make a great Rant title.

PMRpro profile image
PMRproAmbassador

Delightful!

in reply to PMRpro

I thought so! 😬

CT-5012 profile image
CT-5012

Well there we are, alternatively sane. 😱😂

in reply to CT-5012

Agreed! 🙃

podo profile image
podo

An excellent book just published, "The Inflamed Mind" by Edward Bullmore expounds the theory of mental problems having a physical cause, eg; bodily inflamation can be responsible for depression. A good read but don't burden your poor GP with it just yet! Maybe in another decade or so.....

in reply to podo

🤣 "....don't burden your poor GP just yet."

CT-5012 profile image
CT-5012

PS Who took the photo of me this morning? 😂

Primarose profile image
Primarose in reply to CT-5012

Love the hair-do but that teddy bear you are holding looks a bit suspect!;-)

in reply to CT-5012

🤣🤣🤣🤣

scats profile image
scats

I'm in two minds about this one! Is this really what you read first thing in the morning? It takes me hours to get to this level.

in reply to scats

Hahahaha, it is! Sad, huh?

nevagivup profile image
nevagivup

"Psychosis is a mental health problem that causes people to perceive or interpret things differently from those around them. This might involve hallucinations or delusions."According to the NHS:

nhs.uk/conditions/psychosis

So, maybe we are hallucinating that we have a disease and are deluding ourselves we are in pain. Absolute tosh!

Methinks the blogger who wrote that article is somewhat deluded?

Primarose profile image
Primarose in reply to nevagivup

Or maybe he was hallucinating!!!;-)

in reply to Primarose

....or just possibly, to Podo's comment, there might be something to it!

Google "is mental illness linked to autoimmune 2018." You will find numerous articles, by various well established, credible sources who are report and commenting on this research!

Hey, if there is any truth to it.... I'd want to know!

Rimmy profile image
Rimmy

I worked many years ago as a Psych nurse and as tempted as I am to say that I have always been 'stark- staring' I know that I am not. This MUST be 'true' as my GP told me the other day at least half his patients 'weren't sane'... to which i responded - 'but do you think WE are 'sane' !? - and he replied 'Yes 'we' are both sane !!! I laughed at the time but realised later I should have got him (while the going was good) to document that statement and clearly rubber stamp it - for future use of course.

Jokes aside - obviously we are material and physical (chemical/biological) 'beings' and can hardly be surprised that any illnesses or diseases we have are not merely confined to one 'part' or aspect of ourselves - systemic causes/consequences are on the cards. Good news - at least it appears - is that most of us here are not 'psychotic' quite yet .... ?

PMRpro profile image
PMRproAmbassador in reply to Rimmy

However - when half a population "isn't sane" - doesn't that alter the boundaries for sanity?

Rimmy profile image
Rimmy in reply to PMRpro

Sure makes any 'definition' difficult - and it all depends 'which half' we think we are in ..

PMRpro profile image
PMRproAmbassador in reply to Rimmy

I think I'm insane...

Primarose profile image
Primarose in reply to PMRpro

We could start a new club: The "insane freaks".;-)

in reply to Primarose

Love it!

in reply to PMRpro

I know I am.

in reply to PMRpro

Makes sense to me! The boundaries need to be adjusted!

in reply to Rimmy

I agree, and believe it might be a wee bit narrow minded to unequivocally believe that there can be no connection.... like I said, if there's any truth to it, I'd want to be aware!

So instead of blaming it on the Pred, I can blame it on my schizophrenia! 🙃

Angiejnz profile image
Angiejnz

I now know why my behaviour hasn't changed, or at least no-one has noticed a difference. I know I'm completely bonkers, was before pmr and will be afterwards too. Does this make the Good Ship PMR more of a hospital cruise?

in reply to Angiejnz

🤡

Not Electric Compulsive Therapy again surely!!! What a load of cobblers this bull is! You do wonder why some people want to be psychologists!

Angiejnz profile image
Angiejnz in reply to

I suppose they're the modern day version of bards, telling fanciful stories that make them sound important. Maybe they are the new Brothers Grimm??

in reply to Angiejnz

Some do seem to have an angle/edge in their own perspective! Stat's you can do anything with! Ah! It's the power of the name & get a dozen in a room & see how life is so agreeable!

in reply to

Perhaps.... but there is a lot out there (on Google) about research being done by seemingly, credible researchers: and the research is being looked at and reported on by sources like Kings Cross Hospital, The BBC, ScienceDaily, even the NHS reported on it back in 2016. Ya never know!

in reply to

Does't seem helpful research to condition suffers Melissa! What can you do about their conclusions! They have no solution only possibly stating the bleeding obvious which ain't very helpful! ATB

in reply to

Hmmmm? Maybe, but personally, I would want to know, just for the sake of knowing. Just like I want to know all the possible side effects of the meds I take... I'd want to know if the diseases I have, are linked to (or could potentially be linked to) other illnesses. ...but that's just me.

in reply to

I know that feeling too! All different we are. Comes a point though when you have to let go of the medical propaganda! For me anyway.

in reply to

... assuming it's propaganda.

in reply to

Who knows! Lots of self serving research goes on for an earner! As my elders use to say! We're just "Guinea Pigs". I laughed then. Times change but I see the point now! No one Knows really.

peace_lover profile image
peace_lover

Hmmm... I note the subjects were Danish. Bloody Vikings, been causing trouble since 793AD.

in reply to peace_lover

🤣🤣🤣

karools16 profile image
karools16

Haven't read article yet. Pic reminds me of nursery rhyme;

There was a little girl who had a little curl

right in the middle of her forehead;

when she was good

she was very very good,

but when she was bad

she was horrid!...............

GOOD_GRIEF profile image
GOOD_GRIEF

Or, perhaps, insanity is simply the mind's natural protective reaction to the utter absurdity of reality.

Chihuahua1 profile image
Chihuahua1 in reply to GOOD_GRIEF

Very profound! 👏😍

Oooooooo, I like it!!!!!

teesher profile image
teesher

Well, the gang on here all seem perfectly sane, in fact more so because we are so tuned in to our bodies. Hmmm come to think of it, I'm in two minds now...

PMRpro profile image
PMRproAmbassador in reply to teesher

Don't fall out about it though ...

Rimmy profile image
Rimmy

I know we all like to joke (I do this often myself) about how 'bonkers' and/or 'eccentric' we all are - but serious psychosis is of course no laughing matter - it can be very very tragic for those afflicted - just saying ....

in reply to Rimmy

You don't say!

Angiejnz profile image
Angiejnz in reply to Rimmy

Well sometimes they are...I have a sister living in Sweden with schizophrenia and amongst the pain there are some real belly ache laugh moments. Humour is a coping strategy that's more pleasant than some of the others so I try not to take things too seriously.

Yes... of course Rimmy, you're right. It is no laughing matter.

For me, and I can only speak for myself, making light/joking about something like this (Schizophrenia associated with autoimmune disease) is my way of best dealing with the even possible reality that this research might be valid! One of my biggest fears is losing my mental capacity due to a mental illness! It's a wee bit disconcerting to see potentially valid "research" that says I may be one, teeny, tiny step closer to my biggest fear!!!! If I don't laugh... I may cry!!!!

Rimmy profile image
Rimmy in reply to

Of course I understand that and as I said I joke about this myself for similar reasons - and my own fears - but I think though there may be others - possibly silent ones even here on this forum who are struggling right now and it is important to acknowledge this. I didn't mean to sound quite so 'sanctimonious'.

X

in reply to Rimmy

You did not sound sanctimonious at all!!!! You made a valid point and you are RIGHT! There very well may be people on this forum who are struggling (right now) and it is very important to acknowledge that struggle!!!

Rimmy profile image
Rimmy in reply to

Thanks Melissa !! - I am going to Direct Message (Chat) you

X

whisperit profile image
whisperit

Thanks for that report, mamici1. As a visitor from the eminently sensible LupusUK part of this site ;) I'd just like to point out that 1. the association reported is rather small 2. correlation is not causation 2. even so, it would be a bit odd if people with chronic, systemic inflammatory disorders PLUS the significant quantities of meds they have to take as a result were able to withstand that level of assault on their physiology without any significant impact on mood and perception. Frankly, in the circumstances, I'm amazed that any of us function as well as we do. x

maria40 profile image
maria40 in reply to whisperit

Not to mention the contradictory advice of GPs, consultants and other medical specialists which we struggle to come to terms with. I think we deserve medals for retaining what sanity we do have, together with a robust sense of humour which is so evident here.

HI and welcome! How's life in the "eminently sensible LupusUK?"

Perhaps.... I'll just file it away for now. I've set up a Google Alert for future articles; we'll see what, if anything, transpires down the line. : )

whisperit profile image
whisperit in reply to

Oh, interesting times, mamici1, interesting times.....and was that a giant baby I just saw floating overhead....?

in reply to whisperit

Hahahahahahahahaha

HeronNS profile image
HeronNS

Anyone alive in the modern world who isn't insane has something wrong with them.

pmrkitty profile image
pmrkitty

I think we all have to be a little crazy to have this disease, deal with everything that comes with it and still be able to live our lives and laugh about it! Keep smiling even if people are looking at you like you're a little whacko! It makes them wonder what you've been up to. :)

nevagivup profile image
nevagivup

nhs.uk/news/mental-health/s...

The autoimmune disorder/s trigger the psychosis? Not the psychosis trigger the autoimmune disease?

Dunno about anybody else, but I KNOW I am sane, it's t'others I worry about :)) Heeeee!

PMRpro profile image
PMRproAmbassador in reply to nevagivup

Psychosis can be due to an autoimmune disorder?

HeronNS profile image
HeronNS

If there is anyone who can understand this article, I can't, here you go:

sciencedirect.com/science/a...

in reply to HeronNS

Ouch! My brain hurts... I searched for 20 minutes just trying to understand the difference between "neurological" autoimmune disorders and "non"-neurological autoimmune disorders and could not get a straight answer to that!!

Examples of neurological autoimmune disorders >>>> "Multiple sclerosis, myasthenia gravis, and Guillain-Barré syndrome are neurological diseases induced by abnormal autoimmunity."

Examples of NON- neurological autoimmune disorders >>>> ??????????

PMRpro profile image
PMRproAmbassador in reply to

PMR, GCA, RA, diabetes for a start off the top of my head.

But there is a table in the link: Table 2 lists all the NNAI disorders they looked at, starting about half way down it:

alopecia, pernicious anaemia, ankylosing spondylitis, coeliac, Crohns, Graves, pemphigoid, PMR, psoriasis, RA, SLE (one form of lupus), Type 1 diabetes, ulcerative colitis.

in reply to PMRpro

So all of the above you mentioned are examples of a "NON- neurological" autoimmune disorders?

PMRpro profile image
PMRproAmbassador in reply to

Yup.

Chihuahua1 profile image
Chihuahua1 in reply to

pernicious anaemia, psoriasis, rheumatoid arthritis, spondylitis and coeliac disease are some non-neurological disorders. To give a very basis explanation, any autoimmune disease that involves the brain and nerve pathways is considered neurological and those that involves muscle, or organs etc and not the nervous system are non-neurological

PMRpro profile image
PMRproAmbassador in reply to HeronNS

On the basis of looking at a load of smaller studies, there does appear to be a connection between a/i disease and psychosis but it is very variable - in general, as a whole patients with an a/i disorder are more likely to develop a psychosis than those who don't have an a/i illness. However, some a/i disorders seem more likely to be associated with psychosis than others. It also isn't possible to identify which factors are key - i.e was it the disease or was the corticosteroid therapy, for example? Or even, the severe infections that some a/i patients are prone to because of the illness/therapy.

But I would say the biggest connecting factor is inflammation. And Twopies comment about diet could link to that.

A meta analysis of meta analyasis's concluded no real conclusions are ever come too! Since the measurement of gobbledygook is at best, weeing into the wind!! E=mC2!

Twopies profile image
Twopies

Interesting. Back in the early 70s there was a researcher who posited that mental illness was a result of food intolerances in the body—he claimed to have cured patients left and right by changing their diets. Although he supposedly has been debunked, I always thought his theories had some basis in reality. We have much to learn about the human body.

in reply to Twopies

Hi. Amazing how what is defined a "mental illness" has changed over the years! It's not exactly fixed in stone I feel! Very true about the human body plus mind/brain/emotion connection. We are a heaving mass of different perspectives! As much as we don't like it! My view for the moment! ATB

HeronNS profile image
HeronNS in reply to Twopies

There's evidence that people who work night shifts are more prone to serious disease including cancer. It's now being thought possible it's because there's more than one "clock" in the body, and it's the quick adaptation of the gut to a change in schedule which puts it out of sync with the master clock of the brain, and means that metabolites resulting from our digestion are floating around not being used by the systems which normally would, (because they are still asleep) and are therefore causing harm. So I think it's more than likely the gut biome influences brain processes a lot more than we've understood in the past.

Twopies profile image
Twopies

Oh I couldn’t agree more.

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