Decadron/prednisone combo ?

[30048]

I saw mr endrocronlogist yesterday about my prednisone non absorption. I was not able to tolerate the decadron. I had two bad falls , plus mental issues, plus not sleeping. We went back to prednisone, crushed . Well that did not work very well as I ended up in the hospital. The doctor there suggested self administered shots which she was not open to. We decided to rotate the medicine. I day of 1 mg decadron and then two days of prednisone. I do seem to absorb the decadron. Seems a little crazy to me but I am open to suggestions. ( I was on 15 mg. Prednisone and had 2.7 cortisol levelwhen I went to the ER. Was moved to 25) her advice was to keep moving the prednisone lower if the decadron was keeping me stable. One note. I was kept at the hospital due to the fear that I was having a heart attack...

[PMRpro Ambassador]

What on earth is wrong with trying intramuscular methylprednisolone? Or liquid formulations of a corticosteroid. I'm assuming the absorbance problems are associated with the fillers in the tablets which is probably what happened to me.

[30048 in reply to PMRpro]

Thank you. Again !! Never thought of the fillers . I will get a prescription for the liquid and see how that works. I have the liquid decadron but not prednisone.

[PMRpro Ambassador in reply to 30048]

Sometimes even pred from a different manufacturer makes a difference. It applies to many medications.

[karools16 in reply to PMRpro]

PMRpro. I am glad you have said that different manufacturerers of Pred, make a difference. I was amused, yesterday, when my pharmacy delivery man brought my Pred. I always open the packet, to see if correct. I sighed when I saw it was a different'brand', and said I was sure they make a difference. To which he replied, that they must be ok, seeing that I looked so well on them!