Has anyone been on both drugs and which worked better. Worst blood work in two years when was on 60 mg. and can't get below 32 without having a flare. Had biopsy dec. 2014 Thinking of the IV done at hospital once a month for the actemra. Having a lot of stomach issues so worried about the Methotrexate, plus only one working kidney, scares me. Been tryng so hard to wean down, but just not working. Thank you for any info you can give. me.