Hi. I'm new here.... Does anyone know if there is a conflict of interest between Prednisolone and BCG treatment for bladder cancer? I was diagnosed with bladder cancer Nov 2015, had the tumour removed Dec 2015 and began 6 weeks of BCG treatment (a treatment instilled directly into bladder once a week - it is thought to stimulate the immune system to fight off cancer cells) in May 2016. A month after the 6th BCG treatment, mid July, I began with increased pain in my shoulders (I have suffered shoulder pains/aches for 12 months now - I was diagnosed with Fibro in July 2015!). My GP sent me for a blood test which revealed high levels in ESR and C-Protein, which he thought indicated PMR, so I began with 1 week of 40mg Pred - the shoulder pain (in fact all pain) had disappeared within 2 days. The following week the dose was reduced to 20mg, still no pain, so this week reduced to 10 mg. All good so far - BUT my concern is I believe there could be a counter effect by Prednisolone (which I think dampens down the immune system?) on the BCG treatment, which I need to continue to receive 3 weeks of maintenance treatment every three months. I don't want to give up the Prednisolone as I haven't felt so good for 15 months but equally I cannot afford to let the BCG treatment be compromised. Does anyone have any knowledge of this?