Hi everyone, it is so great to have this forum, PMR is such a lonely journey as it is so misunderstood by non sufferers. I have red hair, (now faded!) and read a fascinating article about redheads and medication, in particular pain relief not working. I have never had total pain relief from taking painkillers, except once from morphine for a broken ankle after surgery......! Just wondering if this theory may reflect on my PMR, after 2 years am down to 7mg but in a lot of pain and very stiff. Would hate to have to increase again. Thanks for reading, and regards to all.