A year ago, my GP put me back up to 10mg pred because my CRP wasn't reducing as it should. It stayed stubbornly high-ish all last year, but I have maintained my pred reduction. Now I might have found an explanation for the raised CRP: last year I had very painful sinusitis, flu and a streaming head cold in close succession and have had a blocked nose ever since, despite various solutions by different GPs. Finally I was sent to a consultant last week and he immediately diagnosed a chronic sinus infection - which I could have told him. I suspect that a chronic infection could push up my CRP and hope that is the reason. I now have six weeks of antibiotics, nose drops, nasal rinse - you name it - and am beginning to be able to breathe with my mouth closed. I hope that now I can stop blaming my PMR for raised inflammatory markers and keep going with the pred reductions - currently almost down to 4.5 on very, very slow procedure.