I am beginning my third year of PMR and prednisone. My recent blood work shows my CRP is still at 25. It's never been below 25. Shouldn't the prednisone be lowering this level of inflammation? It doesn't seem to be so what should I do? I am currently taking 9 mg. Pred reducing from 10 two weeks ago. I hurt all over - neck, shoulders, arms, hips, lower back and knees. I know some of the pain in Fibro. Today I feel almost flu-like - I ache. This is all very frustrating.