Hi I was taken off methotrexate,as it didn't do anything for me, and started on Azathriaprine. Two weeks at 50mg then after 1 week on 10g I became really poorly with the chills (shivering and not able to get warm), constant headache, sweats, rapid breathing, loss off appetite and generally feeling unwell. I thought it might be a virus or something but no temperature, blood pressure ok, oxygen levels good etc. So Doc advised to stop Azathriaprine for a couple of days. By the same evening, as stopping the Azathriaprine, I felt a lot better and even ate my dinner. Woke this morning and feel almost normal so will give it a couple of days off the Azathriaprine and then start again (not looking forward to that). Still on 25mg of steroids by the way. Happy Christmas to all of you and I hope 2015 brings you some relief.