Dupuytren's contracture, also called Dupuytren's disease, is a progressive thickening and tightening of the connective tissue in the palm. As it progresses, nodules form and become cords, which eventually pull the fingers into a bent position. Sometimes small callouse looking pads are visible on the knucles. I remember my dad having them!
It is apparently more common in northern european males over 50. There are four instances on my dad's side of the family (originally from North East England UK.) My father and his older brother had it and surgery to remove nodules and release bands. I also have two female cousins 60yrs plus who have this . I am wondering if there is a genetic connection somewhere between - PBC - Dupuytrens - NE England/Scandinavia etc. Also as a matter of interest i have two female cousins late 50's and 60's one of whom has Reynauds and the other recently diagnosed with Rheumatoid Arthritis
By the way, I have read of a connection between alcoholic cirrhosis and dupuytrens. I wondered if there is a connection with any kind of cirrhosis and dupuytrens. (pronounced du-pwe-tranz)