HRT hormone replacement therapy

[Purdy2017]

hi everyone

question is it safe to take hrt with having pbc kind regards Lorraine

[butterflyEi]

this was discussed on one of the Q&A hosted by the PBC Foundation, unfortunately I cannot remember the date of the discussion but I do remember that the answer was it was okay but if I remember correctly there was a preference for the patches.

Professor Jones, OBE is the guest speaker this week if you wanted to you could send in your question for the Thursday Q&A.

best wishes

[Purdy2017 in reply to butterflyEi]

Ok thankyou I did try patches but it brought my skin up so I'm on tablets why did thay favour the patches x

[butterflyEi in reply to Purdy2017]

Sorry Lorraine I do not know but certainly worth asking the questionif you are able to, if you are busy at 1400 hours on Thursday you can always listen in on catch up assuming that you use Facebook. I believe it is handy to email the questions in advance of the day.

That was a nuisance that the patches brought your skin up, pretty sure though tablets are also okay, it has to fall into the category of quality of life, the menopause can be dire for some of us. It is long behind me now but it was not a good time!

best wishes

[Purdy2017 in reply to butterflyEi]

Thankyou yes my skin was really sore and crusty on the edge nasty yes my hot flushes have taken of and its horrible the joy of getting older yes I'm on the face book page group for pbc do thay have the video chats on there x

[Michi1 in reply to Purdy2017]

My doctor just prescribed a tablet you insert in your vagina at night twice a week. Can't tell you how it is because the pharmacy had to order it and I haven't started yet. There are also vaginal creams. That would eliminate the skin issue with the patch while still being "topical" delivery.

[Purdy2017 in reply to Michi1]

Hi thankyou for your reply I've started tablets hope you get on well with your creams and such

[HB70 in reply to Purdy2017]

I was told it had to be patches because they are absorbed straight into the skin whereas tablets have to go through your liver and are therefore not suitable if you have PBC.

[Purdy2017 in reply to HB70]

Not sure I will find out I have to get in contact with them again so I will ask thankyou for your reply

[gwillistexas in reply to Purdy2017]

I had my hysterectomy at 41. My GYN said he would never prescribe the tablets to his patients because they are processed through the liver. I wore the Vivelle Dot patch for years and that was 25 years before I was diagnosed with PBC. They worked well for me. Best I remember, that particular patch is estrogen only. He said when you prescribe estrogen plus progesterone it can pose a problem especially for those who have breast cancer in the family.

[Purdy2017 in reply to gwillistexas]

Ok interesting I have a chat to my doctor this week thankyou for your reply

[gwillistexas in reply to Purdy2017]

After I posted, I looked it up. It does have a warning for those with liver disease. Let us know what your dr says.

[Purdy2017 in reply to gwillistexas]

Ok I will definitely x

[Purdy2017 in reply to gwillistexas]

Hi yes I read the same she didn't say anything she bypassed it and said there are creams and gel you can use so I've decided to go on the spray

[gillrich in reply to butterflyEi]

Brilliant suggestion

[butterflyEi]

On Thursday at 1400 hours UK time if you go to the PBC Foundation's facebook page you can participate live alternatively if you go to the PBC Foundation's link that I have shared here you can join privately.

best wishes

Thursday 21st July 2022 @ 2pm – Robert J Mitchell-Thain & Professor David Jones OBE

Event URL: pbcfoundation.clickmeeting....

Event ID: 769-692-265

[Purdy2017 in reply to butterflyEi]

Thankyou so much you have been a great help x

[iagra]

Absolutely, it is safe. I've been on HRT since 1993. I've been on URSO for PBC since 2016. I take both pills in the morning together. There is no drug interaction between the two meds. I've researched it thoroughly, when I started on URSO.

[Purdy2017 in reply to iagra]

Oh ok that's put my mind at rest could I ask since tacking hrt did it give you back ache in the first couple of weeks I remember that with the paches it did I've just been on tablets for a week and I have back ache again and my womb fills quite stiff to ?

[iagra in reply to Purdy2017]

I never used a patch. I was taking Premarin tabs for many years, then switched to generic estrogen, because of the cost of Premarin. Both type of meds worked the same for me and I never had issues with back pain or anything else that I could connect to taking these meds.

[Purdy2017 in reply to iagra]

Thankyou for your kind reply

[Wocket]

I was told that patches doesn’t go through the liver quite the same way as if you ingested hrt. I was unable to use patches because I didn’t stop bleeding and was told there was no alternative. I now use ovestin which is a hormone cream but that is very localised.

[Purdy2017 in reply to Wocket]

Hi I've just started the paches but my back is hurting and my womb is quite stiff to same happened with the paches hot flushes are unbearable it's bad enough putting up with the fatigue x

[Purdy2017 in reply to Wocket]

Thankyou for your reply I'm going to ask about the craem when I speak to them next as it helped the hot flushes kind regards

[LorraineLouise]

I too have been taking HRT along with my Urso for years. No issues

[Purdy2017 in reply to LorraineLouise]

Hi thankyou for your reply are you taking tablets?

[gillrich]

I had the patches as tablets altered my blood results

[coronavirus19]

Hi i am 68 and have been on hrt since i was 51 i was diagnosed with pbc 12 years ago and no problems. i also have very very dry eyes and arthritis now in spine and shoulders and knees

[CeeCee101]

My PCP has me on compounded HRT both estrogen and progesterone which are compounded specifically for me. In the US not covered by insurance but not very expensive. She has me on it because, like many PBC patients, my bone density was getting worse. It also won’t go through the liver, these are creams. You have to take 4 hours away from URSO. Anyway works for me and seems to help on the bone density.