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PBC Foundation
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Period 10 Days Late(and trying for a baby)


Hope someone has some advice. I was diagnosed with OBC about 2 months ago. Been taking Urso for about a month and a half. I've been trying to get pregnant for 2 years. My cycle is regular as clock work so naturally when I didn't have my period, thought I was pregnant. Did a test, negative. 10 days later and I have just gone on. I'm NEVER late!

Can Urso affect my monthly cycle? Does PBC affect a monthly cycle. So confused and fed up! My skin has become increasingly itchy too so wondered if there's a link.


2 Replies

Hello mrsreddave.

I was 46 when I was diagnosed with PBC December 2010. I still had a cycle and it continued as normal after starting the urso.

Could be the stress of being diagnosed with PBC and perhaps other things going on in your life. Back in 1989 after I had my 2nd and final child who was 8mths old I encountered 2 months where I had no periods. At the time my late former husband got sick and that was the reason my GP gave me after having me take a pregnancy test. Along with some weight loss at the time due to the strain of a sick husband a young baby and a 2yr old (and my mother had passed away only 12 month prior) this was the explanation. In my case I had my normal cycle restored after a 2 month break.

I am not sure if PBC affects the monthly cycle.

I thought the itching for me was a bit worse after starting the urso. I was diagnosed due to intense itching early 2010 so for me I already had it when I started taking urso. Unfortunately with PBC seems a lot of us start with the itch and this then leads to diagnosis of PBC or in some it starts after diagnosis at some point and some lucky ones never itch at all with PBC.


Yes, the itch is part of PBC for most of us. But the messed up cycle I've not had a issue with. I do remember when I was married we tried for a year to have a baby. Just the stress alone was enough to get my cycle out of wack. Just curious, have you discussed trying for a baby after being diagnosed with PBC with your specialist? I hope that's ok for me to ask, feel free to message me if you'd like. Sometimes I feel like what I put on here might offend someone or that Im getting too personal. Im only concerned 😟


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