Hi, I am new to this community. I was diagnosed with PBS 2 months ago. I have had many questions. I deal with the fatigue occasionally, but am currently dealing with really bad itching. My scalp itches my legs, arms face almost all over. My doctor did give me Cholestrymine, for the itch. I tried it this morning, didn't seem to help, I took a shower and smothered "gold bond" medicated powder on and took another does of the cholestrymine, then it did help . Any suggestions with dealing with the itching?